Ultra High Performance Liquid Chromatograph (UHPLC)

Ultra high-performance liquid chromatography, UHPLC, uses columns packed with porous sub-2-µm particles (usually 1.8 µm) to vastly increase throughput and resolving power compared to conventional 5-µm columns. Pressures can surpass 19,000 psi. Limited solvent consumption, the ability to work under a broader pressure range, and lower band broadening are further enhancements. UHPLC’s 10× reduction in analysis time strengthens its popularity in areas including the pharmaceutical industry, food safety, and the clinical field. The choice of detectors for use with UHPLC is wide-ranging, including UV-VIS, fluorescence, photodiode array, ELSD, quadrupole, and most recently, refractive index. For flexibility, many instruments offer the ability to run both conventional and UHPLC on one instrument. A final tip: When making the switch from HPLC to UHPLC, resist the temptation to overload the smaller columns.

Discover and compare Ultra High Performance Liquid Chromatographs:

CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific Vanquish Inverse Gradient LC SystemThermo Scientific Vanquish Neo UHPLC SystemThermo Scientific™ Transcend™ LX UHPLC SystemsVanquish™ Horizon UHPLC SystemVanquish™ LC Systems
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Catalog NumberIQLAAAGABHFAPUMZZZIQLAAAGABHFAPUMBMPIQLAAEGACWFAKWMZZZIQLAAAGABHFAPUMZZZIQLAAAGABHFAPUMZZZ
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DescriptionOur portfolio of innovative and dependable liquid chromatography (LC) instruments includes analytical HPLC and UHPLC systems to handle any separation challenge from simple to complex samples; application-specific HPLC and UHPLC systems for applications such as 2D-LC and dual LC; and nano-, capillary... Read MoreFor researchers pursuing the next scientific breakthrough, the Vanquish Neo UHPLC system delivers maximum performance 24/7 for nano, capillary, and micro-flow LC-MS. Thermo Scientific™ ProFlow™ XR 1500 bar pump technology ensures excellent retention time precision from nano-flow up to 100 µL/min, ... Read MoreImprove your LC-MS throughput and get faster return on investment with the Thermo Scientific™ Transcend™ LX Multichannel UHPLC Systems. The unique multichannel technology included within this UHPLC system increases mass spectrometer utilization by engaging up to four separate LC channels combined ... Read MoreThe Thermo Scientific™ Vanquish™ Horizon UHPLC System is built from the ground up to deliver better results with superior separations and easier interaction with no trade-offs in performance, robustness, or ease-of-use. This fully integrated and biocompatible system features high sample capacity for... Read MoreToday’s scientists deserve the best analytical tools available; tools that empower to achieve the next scientific breakthrough, measure the previously unmeasurable or deliver outstanding quality results dependably. The Vanquish systems improve performance and repeatability with no trade-offs in ... Read More
QuantityEAEAEAEAEA
Detector(s)InquireInquireInquireInquireDiode Array
Flow RateInquireInquireInquire8 mL/min8 mL/min
Max. PressureInquireInquireInquireUp to 1500 bar (22,000 psi)up to 1000 bar (15,000psi)
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