Ultra High Performance Liquid Chromatograph (UHPLC)

Ultra high-performance liquid chromatography, UHPLC, uses columns packed with porous sub-2-µm particles (usually 1.8 µm) to vastly increase throughput and resolving power compared to conventional 5-µm columns. Pressures can surpass 19,000 psi. Limited solvent consumption, the ability to work under a broader pressure range, and lower band broadening are further enhancements. UHPLC’s 10× reduction in analysis time strengthens its popularity in areas including the pharmaceutical industry, food safety, and the clinical field. The choice of detectors for use with UHPLC is wide-ranging, including UV-VIS, fluorescence, photodiode array, ELSD, quadrupole, and most recently, refractive index. For flexibility, many instruments offer the ability to run both conventional and UHPLC on one instrument. A final tip: When making the switch from HPLC to UHPLC, resist the temptation to overload the smaller columns.

Discover and compare Ultra High Performance Liquid Chromatographs:

CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific™ Transcend™ LX UHPLC SystemsThermo Scientific Vanquish Inverse Gradient LC SystemThermo Scientific™ Transcend™ DSX-1 SystemVanquish™ Horizon UHPLC SystemVanquish™ LC Systems
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Catalog NumberIQLAAEGACWFAKWMZZZIQLAAAGABHFAPUMZZZIQLAAEGACWFAKWMBMMIQLAAAGABHFAPUMZZZIQLAAAGABHFAPUMZZZ
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DescriptionImprove your LC-MS throughput and get faster return on investment with the Thermo Scientific™ Transcend™ LX Multichannel UHPLC Systems. The unique multichannel technology included within this UHPLC system increases mass spectrometer utilization by engaging up to four separate LC channels combined ... Read MoreOur portfolio of innovative and dependable liquid chromatography (LC) instruments includes analytical HPLC and UHPLC systems to handle any separation challenge from simple to complex samples; application-specific HPLC and UHPLC systems for applications such as 2D-LC and dual LC; and nano-, capillary... Read MoreRedefine the traditional, labor-intensive, dried matrix spot analysis workflow with the Thermo Scientific Transcend DSX-1 UHPLC system. The fully automated system for toxicology and anti-doping laboratories enables automation and efficient online extraction and enrichment, while delivering sample ... Read MoreThe Thermo Scientific™ Vanquish™ Horizon UHPLC System is built from the ground up to deliver better results with superior separations and easier interaction with no trade-offs in performance, robustness, or ease-of-use. This fully integrated and biocompatible system features high sample capacity for... Read MoreToday’s scientists deserve the best analytical tools available; tools that empower to achieve the next scientific breakthrough, measure the previously unmeasurable or deliver outstanding quality results dependably. The Vanquish systems improve performance and repeatability with no trade-offs in ... Read More
QuantityEAEAEAEAEA
Detector(s)InquireInquireInquireInquireDiode Array
Flow RateInquireInquireInquire8 mL/min8 mL/min
Max. PressureInquireInquireInquireUp to 1500 bar (22,000 psi)up to 1000 bar (15,000psi)
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