Ultra High Performance Liquid Chromatograph (UHPLC)

Ultra high-performance liquid chromatography, UHPLC, uses columns packed with porous sub-2-µm particles (usually 1.8 µm) to vastly increase throughput and resolving power compared to conventional 5-µm columns. Pressures can surpass 19,000 psi. Limited solvent consumption, the ability to work under a broader pressure range, and lower band broadening are further enhancements. UHPLC’s 10× reduction in analysis time strengthens its popularity in areas including the pharmaceutical industry, food safety, and the clinical field. The choice of detectors for use with UHPLC is wide-ranging, including UV-VIS, fluorescence, photodiode array, ELSD, quadrupole, and most recently, refractive index. For flexibility, many instruments offer the ability to run both conventional and UHPLC on one instrument. A final tip: When making the switch from HPLC to UHPLC, resist the temptation to overload the smaller columns.

Discover and compare Ultra High Performance Liquid Chromatographs:

CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific™ Transcend™ LX UHPLC SystemsThermo Scientific Vanquish Neo UHPLC SystemVanquish™ Flex Binary UHPLC SystemVanquish™ Horizon UHPLC SystemVanquish™ LC Systems
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Catalog NumberIQLAAEGACWFAKWMZZZIQLAAAGABHFAPUMBMPIQLAAAGABHFAPUMBJCIQLAAAGABHFAPUMZZZIQLAAAGABHFAPUMZZZ
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DescriptionImprove your LC-MS throughput and get faster return on investment with the Thermo Scientific™ Transcend™ LX Multichannel UHPLC Systems. The unique multichannel technology included within this UHPLC system increases mass spectrometer utilization by engaging up to four separate LC channels combined ... Read MoreFor researchers pursuing the next scientific breakthrough, the Vanquish Neo UHPLC system delivers maximum performance 24/7 for nano, capillary, and micro-flow LC-MS. Thermo Scientific™ ProFlow™ XR 1500 bar pump technology ensures excellent retention time precision from nano-flow up to 100 µL/min, ... Read MoreThe Thermo Scientific™ Vanquish™ Flex Binary UHPLC system is biocompatible with a state-of-the-art binary high-pressure pump and state-of-the-art binary solvent blending. This ultra high performance liquid chromatography system shares all Vanquish values, such as a design focused on uptime, ... Read MoreThe Thermo Scientific™ Vanquish™ Horizon UHPLC System is built from the ground up to deliver better results with superior separations and easier interaction with no trade-offs in performance, robustness, or ease-of-use. This fully integrated and biocompatible system features high sample capacity for... Read MoreToday’s scientists deserve the best analytical tools available; tools that empower to achieve the next scientific breakthrough, measure the previously unmeasurable or deliver outstanding quality results dependably. The Vanquish systems improve performance and repeatability with no trade-offs in ... Read More
QuantityEAEAEAEAEA
Detector(s)InquireInquireInquireInquireDiode Array
Flow RateInquireInquire8 mL/min8 mL/min8 mL/min
Max. PressureInquireInquireup to 1000 bar (15,000psi)Up to 1500 bar (22,000 psi)up to 1000 bar (15,000psi)
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