| Description | See what you've been missing. The highest-performance UPLC system ever engineered, now with a truly inert flow path.
The ACQUITY Premier System represents the most significant advance in separation science since Waters introduced UPLC technology in 2004. Built on the proven ACQUITY UPLC platform — See what you've been missing. The highest-performance UPLC system ever engineered, now with a truly inert flow path.
The ACQUITY Premier System represents the most significant advance in separation science since Waters introduced UPLC technology in 2004. Built on the proven ACQUITY UPLC platform — delivering true Ultra Performance Liquid Chromatography with ultra-low dispersion, sub-2-µm particle compatibility, and best-in-class resolution — it adds a transformative layer of innovation: MaxPeak™ High Performance Surfaces (HPS) Technology. This technology creates a barrier between the sample and every metal surface in the flow path, eliminating the non-specific adsorption that has long plagued analysis of metal-sensitive analytes. The result is sharper peaks, higher recovery, and reproducible results from the first injection — no passivation, no additives, no wasted runs.
Designed holistically alongside ACQUITY Premier Columns and QuanRecovery™ Vials and Plates with MaxPeak HPS, the ACQUITY Premier System delivers a complete end-to-end solution across reversed-phase and HILIC separations for organic acids, organophosphates, oligonucleotides, peptides, glycans, phospholipids, and beyond.
Key Features and Benefits:- MaxPeak HPS Technology throughout the entire flow path eliminates metal-sensitive analyte losses, enabling detection of compounds previously obscured or undetected on conventional LC systems.
- True UPLC performance with ultra-low extra-column dispersion, enabling full exploitation of sub-2-µm column chemistry for superior resolution, sensitivity, and throughput.
- Dramatically reduced system passivation requirements, saving hours to days per assay and lowering reagent costs while increasing lab uptime and productivity.
- Flexible configurations available including Binary Solvent Management for lowest-dispersion LC-MS workflows and Quaternary Solvent Management for broad method development and multi-solvent screening needs.
- Compatible with the full range of Waters detectors — TUV, PDA, FLR — and seamlessly couples with Waters mass spectrometers for confident identification and quantitation of trace components in complex matrices.
- Fully supported in Empower™ CDS, MassLynx™ , and UNIFI™ Software for regulated and non-regulated laboratory environments; ACT environmentally responsible design certification.
... Read More | Right-first-time results for every method, every lab, every analyst.
The Arc Premier System brings the power of MaxPeak™ High Performance Surfaces (HPS) Technology to routine HPLC and UHPLC analysis — delivering a new standard of data quality, reproducibility, and confidence for laboratory Right-first-time results for every method, every lab, every analyst.
The Arc Premier System brings the power of MaxPeak™ High Performance Surfaces (HPS) Technology to routine HPLC and UHPLC analysis — delivering a new standard of data quality, reproducibility, and confidence for laboratory scientists who cannot afford to lose time troubleshooting methods or re-running failed analyses. Optimized for chromatographic separations on 2.5–3.5 µm column chemistry and holistically designed alongside MaxPeak Premier Columns, the Arc Premier System virtually eliminates the non-specific adsorption between sample analytes and metal surfaces that causes peak broadening, poor integration, and inconsistent results — without requiring complex mobile phase additives or laborious conditioning protocols.
Whether deployed for pharmaceutical method development, quality control release testing, food safety analysis, or environmental monitoring, the Arc Premier System delivers the flexibility, regulatory readiness, and analytical confidence modern laboratories demand, right out of the box.
Key Features and Benefits:- MaxPeak HPS Technology provides up to 5x improvement in detector sensitivity, up to 10x improvement in system-to-system reproducibility, and up to 100x improvement in user-to-user reproducibility for metal-sensitive compounds, with potential savings of 2–3 days per assay by eliminating passivation.
- Versatile solvent management with the Quaternary Solvent Manager supporting blending of four to nine solvents in any combination, and the Binary Solvent Manager-R delivering precise blending at pressures up to 9,500 psi across the full flow rate range.
- High-precision flow-through needle injector with a volume range of 0.1–1,000 µL and ultra-low carryover (=0.002%) for confident LC-MS compatibility.
- Advanced column management supporting up to six analytical columns with independently controlled temperature zones, active pre-heating, and eCord™ Intelligent Chip Technology.
- SmartStart gradient technology enables seamless method transfer from legacy HPLC systems — typically in as few as two injections — without requiring gradient table changes.
- Compliance-ready and fully supported in Empower™ CDS and MassLynx™ Software, with automated System Qualification Tool (SQT) to minimize qualification time and cost under GMP, GLP, ISO 17025, and USP <1058> frameworks..
- Compatible with TUV, PDA, and FLR detectors with MaxPeak HPS-equipped flow cells, and mass detection via ACQUITY QDa, SQD2, Xevo TQS-micro, and Xevo TQS-cronos.
... Read More |