Ultra High Performance Liquid Chromatograph (UHPLC)

Ultra high-performance liquid chromatography, UHPLC, uses columns packed with porous sub-2-µm particles (usually 1.8 µm) to vastly increase throughput and resolving power compared to conventional 5-µm columns. Pressures can surpass 19,000 psi. Limited solvent consumption, the ability to work under a broader pressure range, and lower band broadening are further enhancements. UHPLC’s 10× reduction in analysis time strengthens its popularity in areas including the pharmaceutical industry, food safety, and the clinical field. The choice of detectors for use with UHPLC is wide-ranging, including UV-VIS, fluorescence, photodiode array, ELSD, quadrupole, and most recently, refractive index. For flexibility, many instruments offer the ability to run both conventional and UHPLC on one instrument. A final tip: When making the switch from HPLC to UHPLC, resist the temptation to overload the smaller columns.

Discover and compare Ultra High Performance Liquid Chromatographs:

CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific™ Vanquish™ Horizon UHPLC SystemThermo Scientific™ UltiMate™ 3000 Biocompatible Rapid Separation BioRS SystemThermo Scientific™ Vanquish™ Duo UHPLC SystemsThermo Scientific™ Vanquish™ Flex Binary UHPLC SystemThermo Scientific™ Vanquish™ LC Systems
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Catalog NumberIQLAAAGABHFAPUMZZZIQLAAAGADGFAMIMBCOIQLAAAGABHFAPUMZZZIQLAAAGABHFAPUMBJCIQLAAAGABHFAPUMZZZ
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DescriptionThe Thermo Scientific™ Vanquish™ Horizon UHPLC System is built from the ground up to deliver better results with superior separations and easier interaction with no trade-offs in performance, robustness, or ease-of-use. This fully integrated and biocompatible system features high sample capacity for... Read MoreThe Thermo Scientific™ UltiMate™ 3000 BioRS System offers true bio-UHPLC capabilities with completely stainless steel-free flow path and newly developed, small particle and high-resolution bio-columns. Near-zero dead volume, Thermo Scientific™ Viper™ connection technology preserves peak sharpness ... Read MoreUse the Thermo Scientific™ Vanquish™ Duo UHPLC Systems to support four workflows (Dual LC, Tandem LC or LC-MS, Transcend Duo LX-2 and Inverse Gradient) by combining two flow paths in one integrated UHPLC solution. These workflows improve your productivity by saving time, reducing cost per sample, ... Read MoreThe Thermo Scientific™ Vanquish™ Flex Binary UHPLC system is biocompatible with a state-of-the-art binary high-pressure pump and state-of-the-art binary solvent blending. This ultra high performance liquid chromatography system shares all Vanquish values, such as a design focused on uptime, ... Read MoreToday’s scientists deserve the best analytical tools available; tools that empower to achieve the next scientific breakthrough, measure the previously unmeasurable or deliver outstanding quality results dependably. The Vanquish systems improve performance and repeatability with no trade-offs in ... Read More
QuantityEAEAEAEAEA
Flow Rate8 mL/min8 mL/minInquire8 mL/min8 mL/min
Max. PressureUp to 1500 bar (22,000 psi)up to 1000 bar (15,000psi)1500 bar (22,000 psi)up to 1000 bar (15,000psi)up to 1000 bar (15,000psi)
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