Ultra High Performance Liquid Chromatograph (UHPLC)

Ultra high-performance liquid chromatography, UHPLC, uses columns packed with porous sub-2-µm particles (usually 1.8 µm) to vastly increase throughput and resolving power compared to conventional 5-µm columns. Pressures can surpass 19,000 psi. Limited solvent consumption, the ability to work under a broader pressure range, and lower band broadening are further enhancements. UHPLC’s 10× reduction in analysis time strengthens its popularity in areas including the pharmaceutical industry, food safety, and the clinical field. The choice of detectors for use with UHPLC is wide-ranging, including UV-VIS, fluorescence, photodiode array, ELSD, quadrupole, and most recently, refractive index. For flexibility, many instruments offer the ability to run both conventional and UHPLC on one instrument. A final tip: When making the switch from HPLC to UHPLC, resist the temptation to overload the smaller columns.

Discover and compare Ultra High Performance Liquid Chromatographs:

CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific™ Vanquish™ Duo UHPLC SystemsThermo Scientific™ Transcend™ DSX-1 SystemThermo Scientific™ UltiMate™ 3000 Biocompatible Rapid Separation BioRS SystemThermo Scientific™ Vanquish™ Flex Quaternary UHPLC SystemThermo Scientific™ Vanquish™ LC Systems
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Catalog NumberIQLAAAGABHFAPUMZZZIQLAAEGACWFAKWMBMMIQLAAAGADGFAMIMBCOIQLAAAGABHFAPUMBHVIQLAAAGABHFAPUMZZZ
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DescriptionUse the Thermo Scientific™ Vanquish™ Duo UHPLC Systems to support four workflows (Dual LC, Tandem LC or LC-MS, Transcend Duo LX-2 and Inverse Gradient) by combining two flow paths in one integrated UHPLC solution. These workflows improve your productivity by saving time, reducing cost per sample, ... Read MoreRedefine the traditional, labor-intensive, dried matrix spot analysis workflow with the Thermo Scientific Transcend DSX-1 UHPLC system. The fully automated system for toxicology and anti-doping laboratories enables automation and efficient online extraction and enrichment, while delivering sample ... Read MoreThe Thermo Scientific™ UltiMate™ 3000 BioRS System offers true bio-UHPLC capabilities with completely stainless steel-free flow path and newly developed, small particle and high-resolution bio-columns. Near-zero dead volume, Thermo Scientific™ Viper™ connection technology preserves peak sharpness ... Read MoreThe Thermo Scientific™ Vanquish™ Flex Quaternary system provides state-of-the-art quaternary solvent blending. As a member of the Thermo Scientific Vanquish UHPLC product line, the Vanquish Flex Quaternary system delivers new benchmarks in accuracy, precision, and sensitivity with a state-of-the-art... Read MoreToday’s scientists deserve the best analytical tools available; tools that empower to achieve the next scientific breakthrough, measure the previously unmeasurable or deliver outstanding quality results dependably. The Vanquish systems improve performance and repeatability with no trade-offs in ... Read More
QuantityEAEAEAEAEA
Flow RateInquireInquire8 mL/min8 mL/min8 mL/min
Max. Pressure1500 bar (22,000 psi)Inquireup to 1000 bar (15,000psi)up to 1000 bar (15,000psi)up to 1000 bar (15,000psi)
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