Ultra High Performance Liquid Chromatograph (UHPLC)

Ultra high-performance liquid chromatography, UHPLC, uses columns packed with porous sub-2-µm particles (usually 1.8 µm) to vastly increase throughput and resolving power compared to conventional 5-µm columns. Pressures can surpass 19,000 psi. Limited solvent consumption, the ability to work under a broader pressure range, and lower band broadening are further enhancements. UHPLC’s 10× reduction in analysis time strengthens its popularity in areas including the pharmaceutical industry, food safety, and the clinical field. The choice of detectors for use with UHPLC is wide-ranging, including UV-VIS, fluorescence, photodiode array, ELSD, quadrupole, and most recently, refractive index. For flexibility, many instruments offer the ability to run both conventional and UHPLC on one instrument. A final tip: When making the switch from HPLC to UHPLC, resist the temptation to overload the smaller columns.

Discover and compare Ultra High Performance Liquid Chromatographs:

CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemThermo Scientific™ Transcend™ DSX-1 SystemThermo Scientific™ UltiMate™ 3000 Biocompatible Rapid Separation BioRS Dual SystemThermo Scientific™ UltiMate™ 3000 Basic Automated SystemThermo Scientific™ Vanquish™ Flex Binary UHPLC SystemThermo Scientific™ Vanquish™ Horizon UHPLC System
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Catalog NumberIQLAAEGACWFAKWMBMMIQLAAAGABHFAPBMBFFIQLAAAGABHFAPBMBFCIQLAAAGABHFAPUMBJCIQLAAAGABHFAPUMZZZ
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DescriptionRedefine the traditional, labor-intensive, dried matrix spot analysis workflow with the Thermo Scientific Transcend DSX-1 UHPLC system. The fully automated system for toxicology and anti-doping laboratories enables automation and efficient online extraction and enrichment, while delivering sample ... Read MoreThe Thermo Scientific ™ UltiMate™ 3000 BioRS Dual System offers outstanding LC and advanced bio-UHPLC capabilities. Two independently operating gradient pumps and smart column switching save time. Offline fractionation combines noncompatible chemistries in one workflow. With our unique fractionation... Read MoreThe Thermo Scientific™ UltiMate™ 3000 Automated system offers unique LC and entry level UHPLC capabilities without compromise. The integrated autosampler and thermostatted column compartment deliver retention time precision and the ability to fine tune backpressure, resolution and speed. With ... Read MoreThe Thermo Scientific™ Vanquish™ Flex Binary UHPLC system is biocompatible with a state-of-the-art binary high-pressure pump and state-of-the-art binary solvent blending. This ultra high performance liquid chromatography system shares all Vanquish values, such as a design focused on uptime, ... Read MoreThe Thermo Scientific™ Vanquish™ Horizon UHPLC System is built from the ground up to deliver better results with superior separations and easier interaction with no trade-offs in performance, robustness, or ease-of-use. This fully integrated and biocompatible system features high sample capacity for... Read More
QuantityEAEAEAEAEA
Flow RateInquire8 mL/min10 mL/min8 mL/min8 mL/min
Max. PressureInquire103.4 Mpa or 1034 bar or 15000 psi62 Mpa / 620 bar / 9000 psiup to 1000 bar (15,000psi)Up to 1500 bar (22,000 psi)
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