| Description | Alliance iS Bio™ HPLC System
Intuitive, bio-inert, and built for right-first-time results in biopharma routine workflows.
The Alliance iS Bio HPLC System delivers the intuitive simplicity biopharma labs need to keep pace with increasing complexity, stringent compliance requirements, and high sample Alliance iS Bio™ HPLC System
Intuitive, bio-inert, and built for right-first-time results in biopharma routine workflows.
The Alliance iS Bio HPLC System delivers the intuitive simplicity biopharma labs need to keep pace with increasing complexity, stringent compliance requirements, and high sample workloads. Purpose-built for biologics and metal-sensitive analytes, it combines bio-inert flow paths, MaxPeak™ High-Performance Surfaces (HPS) Technology, and intelligent system safeguards to help analysts generate consistent, high-quality data—while reducing common user-driven errors by up to 40%.
Engineered for demanding biopharma applications across proteins, peptides, oligonucleotides, ADCs, conjugates, and high-salt methods, the Alliance iS Bio supports routine release, identity, impurity, and stability testing with superior robustness, reproducibility, and analyte recovery. Its advanced flow-path design decreases carryover by up to two orders of magnitude, delivering the clarity and confidence required for regulated QC environments.
The system boosts performance where it matters most, offering up to 80× out-of-the-box sensitivity, 30% improved sensitivity, and 15% improved recovery—helping labs detect low-level impurities, sharpen resolutions, and reduce repeat analyses.
With guided touchscreen workflows, automated acquisition checks, and full Empower™ CDS compatibility, the Alliance iS Bio HPLC System improves operational efficiency, helps prevent failed runs before they occur, and ensures data integrity throughout every stage of analysis.... Read More | Right-first-time results for every method, every lab, every analyst.
The Arc Premier System brings the power of MaxPeak™ High Performance Surfaces (HPS) Technology to routine HPLC and UHPLC analysis — delivering a new standard of data quality, reproducibility, and confidence for laboratory Right-first-time results for every method, every lab, every analyst.
The Arc Premier System brings the power of MaxPeak™ High Performance Surfaces (HPS) Technology to routine HPLC and UHPLC analysis — delivering a new standard of data quality, reproducibility, and confidence for laboratory scientists who cannot afford to lose time troubleshooting methods or re-running failed analyses. Optimized for chromatographic separations on 2.5–3.5 µm column chemistry and holistically designed alongside MaxPeak Premier Columns, the Arc Premier System virtually eliminates the non-specific adsorption between sample analytes and metal surfaces that causes peak broadening, poor integration, and inconsistent results — without requiring complex mobile phase additives or laborious conditioning protocols.
Whether deployed for pharmaceutical method development, quality control release testing, food safety analysis, or environmental monitoring, the Arc Premier System delivers the flexibility, regulatory readiness, and analytical confidence modern laboratories demand, right out of the box.
Key Features and Benefits:- MaxPeak HPS Technology provides up to 5x improvement in detector sensitivity, up to 10x improvement in system-to-system reproducibility, and up to 100x improvement in user-to-user reproducibility for metal-sensitive compounds, with potential savings of 2–3 days per assay by eliminating passivation.
- Versatile solvent management with the Quaternary Solvent Manager supporting blending of four to nine solvents in any combination, and the Binary Solvent Manager-R delivering precise blending at pressures up to 9,500 psi across the full flow rate range.
- High-precision flow-through needle injector with a volume range of 0.1–1,000 µL and ultra-low carryover (=0.002%) for confident LC-MS compatibility.
- Advanced column management supporting up to six analytical columns with independently controlled temperature zones, active pre-heating, and eCord™ Intelligent Chip Technology.
- SmartStart gradient technology enables seamless method transfer from legacy HPLC systems — typically in as few as two injections — without requiring gradient table changes.
- Compliance-ready and fully supported in Empower™ CDS and MassLynx™ Software, with automated System Qualification Tool (SQT) to minimize qualification time and cost under GMP, GLP, ISO 17025, and USP <1058> frameworks..
- Compatible with TUV, PDA, and FLR detectors with MaxPeak HPS-equipped flow cells, and mass detection via ACQUITY QDa, SQD2, Xevo TQS-micro, and Xevo TQS-cronos.
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