Differential scanning calorimetry analysis provides insight into critical physical properties of materials by testing their response to heat. The heating of both a sample and reference material provides a validated relative temperature response and heat capacity. These furnace-based systems are perfect for studying unique phase-change properties, such as with liquid crystals, determining quantitative enthalpy of materials, or testing the elasticity of products exposed to extreme temperatures and/or pressures. Differential scanning calorimeters offer temperature ranges as low as -180C and as high as 2400C, with the highest available heating rate at 300 K/min for DSC analysis. The principle models utilize heat flux systems, corrosion-free silver furnaces, or cylindrical high-conductivity silver block units, among others. The customer should keep an eye out for a differential scanning calorimeter that suppresses or prevents overlapping vaporization and/or simulates realistic temperature and pressure conditions.
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| Company | TA Instruments – a division of Waters Corporation | TA Instruments – a division of Waters Corporation | TA Instruments – a division of Waters Corporation | TA Instruments – a division of Waters Corporation |
| Item | Rapid Screening-Differential Scanning Calorimeter | Discovery DSC 25P | Discovery X3 Differential Scanning Calorimeter | Nano Differential Scanning Calorimeter |
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| Catalog Number | RS-DSC | DSC 25P | X3 DSC | |
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| Type | Inquire | High Pressure Differential Scanning Calorimeter | Differential Scanning Calorimeter | High-resolution DSC |
| Temperature Range | 20 to 100 °C | -130°C to 550°C | -180°C to 550°C | -10°C to 130°C |
| Heating Rate | Inquire | 0.01 to 100°C/min | 0.01 °C/min to 200 °C/min | Inquire |
| Cooling Rate | Inquire | Inquire | 0.01 °C/min to 200 °C/min | Inquire |
| Description | The Next Generation of Thermal Stability Testing for Biologic Drugs
The TA Instruments RS-DSC (Rapid Screening-Differential Scanning Calorimeter) is a powerful and versatile instrument that revolutionizes the thermal stability testing of biological drugs with its high efficiency and streamlined The Next Generation of Thermal Stability Testing for Biologic Drugs
The TA Instruments RS-DSC (Rapid Screening-Differential Scanning Calorimeter) is a powerful and versatile instrument that revolutionizes the thermal stability testing of biological drugs with its high efficiency and streamlined analysis.
For scientists in the demanding world of biological drug development, understanding biomolecule stability under thermal variations is crucial to ensure product quality, and support regulatory approval. Short-term thermal stability testing reveals a compound’s resilience to thermal stress, predicts shelf life, and ensures efficacy. The requirement for accurately measuring this in a high throughput environment is challenging without disrupting processes or meeting tight timelines. To meet this demand, we designed the TA Instruments RS-DSC (Rapid Screening-Differential Scanning Calorimeter), a new solution for the rapid characterization of biotherapeutic thermal stability.
How the TA Instruments RS-DSC Can Help:
- Accelerate thermal stability testing: The TA Instruments RS-DSC provides detailed insights into drug product thermal stability significantly quicker by analyzing up to 24 samples simultaneously. The TA Instruments RS-DSC’s technology also simplifies the characterization of highly concentrated drug products.
- Improve efficiency: The TA Instruments RS-DSC ensures materials are used efficiently by utilizing disposable MFCs (Micro microfluidic chips) to contain the sample. MFCs require <15 ul sample volume, and the design facilitates a cleaner, more streamlined operation by reducing the need for tedious sample dilution, repetitive instrument cleaning, and contamination risks.
- Make more informed decisions: NanoAnalyze™ Software effortlessly handles the increased data volume produced by the TA Instruments RS-DSC, providing in-depth, precise insights about a molecule’s thermal stability and thermodynamic properties.
... Read More | The DSC 25P is a dedicated Pressure DSC module that provides heat flow measurements on pressure sensitive materials. The Discovery DSC 25P is used to study thermal transitions, chemical reactions and oxidative stability/ decomposition under vacuum, standard atmospheric pressure and elevated The DSC 25P is a dedicated Pressure DSC module that provides heat flow measurements on pressure sensitive materials. The Discovery DSC 25P is used to study thermal transitions, chemical reactions and oxidative stability/ decomposition under vacuum, standard atmospheric pressure and elevated pressures. It measures a materials’ heat flow in a variety of inert, oxidizing or reducing atmospheres.... Read More | TA Instruments invites you to Discover the possibilities with the Discovery X3 Differential Scanning Calorimeter featuring a multi-sample cell that delivers high quality heat flow data for up to three samples simultaneously. The Discovery X3 DSC combines industry-leading performance with the tools TA Instruments invites you to Discover the possibilities with the Discovery X3 Differential Scanning Calorimeter featuring a multi-sample cell that delivers high quality heat flow data for up to three samples simultaneously. The Discovery X3 DSC combines industry-leading performance with the tools to increase productivity on every level of material research. TA Instruments’ commitment to innovation enables scientists and engineers to reach their goals faster and make critical decisions with confidence.
Features: - Fusion Cell™ with patented technology provides unrivaled performance in baseline flatness, sensitivity, resolution, and reproducibility. Its superb technology enables detection of the weakest thermal transitions and the most accurate enthalpy and specific heat capacity measurements.
- Enhanced Tzero heat flow technology for the X3 guarantees temperature and enthalpy accuracy simultaneously on all three samples
- High-end performance with three sample calorimeters provide unmatched flexibility from replicate testing for statistical analysis to validation/verification against a control sample for the ultimate in certainty
- Modulated DSC® (MDSC®) for the most efficient separation of complex thermal events.
- One-Touch-Away™ User Interface enhances usability and access to data on the instrument.
- Reliable linear autosampler with 54 programmable tray positions for worry-free 24/7 operation, flexible programming of experiments, and automated calibration and verification routines.
- Widest range of refrigerated cooling options eliminates liquid nitrogen expense and ensures uninterrupted sub-ambient operation during extended autosampler routines.
- Tzero Press and pans for fast, simple, and reproducible sample preparation.
- Powerful software that delivers an exceptional user experience in a combined package for instrument control, data analysis, and reporting. Features such as automated calibration routines and real-time test method editing provide unmatched flexibility, while One-Click analysis and custom reporting raise productivity to new levels.
- Commitment to quality backed by the industry’s ONLY five-year cell and furnace warranty for peace of mind.
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... Read More | The Nano DSC differential scanning calorimeter is designed to characterize the molecular stability of dilute in-solution biomolecules. The Nano DSC obtains data using less sample than competitive designs. Solid-state thermoelectric elements are used to precisely control temperature and a built-in The Nano DSC differential scanning calorimeter is designed to characterize the molecular stability of dilute in-solution biomolecules. The Nano DSC obtains data using less sample than competitive designs. Solid-state thermoelectric elements are used to precisely control temperature and a built-in precision linear actuator maintains constant or controlled variable pressure in the cell. Automated, unattended continuous operation with increased sample throughput is achieved with the optional Nano DSC Autosampler.... Read More |
| Quantity | EA | EA | EA | EA |
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