A total organic carbon analyzer (also referred to as TOC analyzers) measures the amount of total organic carbon present in a liquid or water sample. TOC detection is important because of the effects that TOCs may have on health, not to mention the environmental effects and implications for the pharmaceutical manufacturing processes. Since all total organic carbon analyzers only measure total carbon, a TOC analyzer always requires some accounting for the inorganic carbon (IC) that is always present.
TOC analyzers, including a portable TOC analyzer, utilize the same basic technique where acid is added to the liquid sample to remove IC. At this point, the IC is converted into carbon dioxide gas. It is then stripped out of the liquid by a carrier gas where the remaining inorganic carbon-free sample is then oxidized and the carbon dioxide generated from the oxidation process is directly related to the TOC total organic carbon in the sample. There are several methods for introducing the sample to TOC analyzers, including using a syringe, autosampler, and loop sampling. An important specification for total organic carbon analyzers is the measuring range. Carrier gas flow rate, average analysis time and process temperature are important as well for total organic carbon analysis.
Find, compare, and request a quote for total organic carbon analyzers (TOC analyzers) across leading suppliers at Labcompare; including access to product citations, related published figures, and first-hand reviews from our scientific community.
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| Company | Shimadzu | Shimadzu | Shimadzu | Shimadzu | Shimadzu |
| Item | TOC-VWS Wet Oxidation TOC Analyzer | TOC-1000e S Online TOC Analyzer | TOC-1000e S Online Total Organic Carbon Analyzer | TOC-4200 Online Total Organic Carbon Analyzer | TOC-VWP Wet Oxidation TOC Analyzer |
| Citations | | | | | |
| Catalog Number | TOC-VWS / TOC-VWP | | TOC-1000e S | TOC-4200 | |
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| Measurement Mode(s) | TC, IC, TOC, NPOC | Inquire | Inquire | TC, NPOC, IC-POC M, TN | Inquire |
| Oxidation Method | Wet Chemical (Heat-UV-Persulfate) | 680°C Combustion Catalytic Oxidation | Inquire | Combustion Oxidation / Non-Dispersive Infrared Gas Detection | Wet Oxidation (persulfate + UV) |
| Measuring Range | TC: 0-3,500 mg/L, IC: 0-3,500 mg/L | Inquire | 0 to 500 µg/L | 5 to 20,000 mgC/L | Inquire |
| Detection Limit | 0.5 µg/L | 0.1 µg/L | Inquire | Inquire | 4 µg/L |
| Sample Volume | 350 to 20400 µl variable | Inquire | Inquire | Inquire | Inquire |
| Measurement Accuracy | CV 1.5% to 2% max | Inquire | ±5% (500 µg/L sucrose) | Within +/-2 % (×2 to ×20); within ±5 % (×21 to ×50) (Dilution accuracy) | Inquire |
| Measuring Time | ~ 4 minutes | Inquire | Inquire | 4 min | Inquire |
| Description | Shimadzu’s TOC-VW can be operated as a UV/Persulfate TOC, a Heated/Persulfate TOC, or as a unique Heated-UV-Persulfate TOC system. The three oxidation methods ensure rapid breakdown of difficult-to-oxidize compounds and shorter analysis times. The analyzer can handle particulates up to 1.6 mm in Shimadzu’s TOC-VW can be operated as a UV/Persulfate TOC, a Heated/Persulfate TOC, or as a unique Heated-UV-Persulfate TOC system. The three oxidation methods ensure rapid breakdown of difficult-to-oxidize compounds and shorter analysis times. The analyzer can handle particulates up to 1.6 mm in diameter, the largest for any commercial analyzer. The TOC-VW has a low detection limit (0.5 ppb) for ultrapure water analyses. Its NDIR detector has five orders of magnitude linearity. Over-range samples can be compared with up to three calibration curves automatically.
Features - Random-access autosampler control
- Multipoint calibration curves in user-selectable concentration
- Each sample can be automatically compared
- High efficiency system with low cost consumables
... Read More | Inquire | As semiconductor miniaturization continues to advance, even trace-level organic contamination in ultrapure water can directly impact process stability and yield, making precise, reliable monitoring of TOC essential. Conventional on-line TOC analyzers often struggle to detect hard-to-oxidize As semiconductor miniaturization continues to advance, even trace-level organic contamination in ultrapure water can directly impact process stability and yield, making precise, reliable monitoring of TOC essential. Conventional on-line TOC analyzers often struggle to detect hard-to-oxidize compounds such as urea, which can persist after purification and compromise fabrication processes. Developed with direct input from leading semiconductor manufacturers, the TOC-1000e S online total organic carbon analyzer addresses these challenges by delivering enhanced sensitivity and real-time monitoring capabilities tailored to next-generation fabrication environments.
Features include:
- High-sensitivity detection of hard-to-oxidize organic contaminants, including urea, promoting more accurate assessment of ultrapure water quality
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Simplified flow path that enables real-time monitoring and rapid response to contamination events
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High-visibility touch panel with intuitive, color-coded status indicators supports efficiency daily operation and data review
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Only requires annual onsite maintenance for maximum uptime
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Supports a variety of data output formats
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Network connectivity allows users to monitor data remotely through a standard web browser without dedicated software
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Compact design weighing approximately 3 kg makes it suitable for benchtop, wall or pipe-mounted installation
... Read More | Shimadzu’s highly advanced on-line TOC-4200 analyzer excels in a wide range of water analysis applications, from continuous monitoring of plant/boiler water and management of wastewater treatment plant influent and effluent to management of the water in manufacturing processes. Advanced Shimadzu’s highly advanced on-line TOC-4200 analyzer excels in a wide range of water analysis applications, from continuous monitoring of plant/boiler water and management of wastewater treatment plant influent and effluent to management of the water in manufacturing processes. Advanced functionality and communication methods, enhanced data handling, and low maintenance and running costs make this an ideal system for numerous applications. The TOC-4200 utilizes Shimadzu's proven, industry-standard 680 C combustion catalytic oxidation method to support analyses from 5 mgC/L to 20,000 mgC/L full-scale. With a high-sensitivity kit, the TOC-4200 can measure samples with TOC concentrations from 0 to 1mgC/L, such as underground water, public drinking water, or recovered deionized water from semiconductor manufacturing.
Features - Multiple pretreatment units to best match a sample’s characteristics
- Multi-functional sample injector – allows for a multipoint calibration curve from a single high standard
- Carrier gas purification function
- High-salt sample combustion tube kit – increases the period between maintenance by a factor of 10
- On-board air purifier
- Touch-screen LCD
The TOC-4200 offers an ECO mode that reduces waste by only using carrier gas and operating the sampling pump when it is needed. In addition, a web-based monitoring function allows users to monitor data and status from any network-connected computer, while a notification system alerts users when reagent or consumable replacement periods approach.... Read More | Inquire |
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