Total Organic Carbon Analyzer (TOC Analyzers)

A total organic carbon analyzer (also referred to as TOC analyzers) measures the amount of total organic carbon present in a liquid or water sample. TOC detection is important because of the effects that TOCs may have on health, not to mention the environmental effects and implications for the pharmaceutical manufacturing processes. Since all total organic carbon analyzers only measure total carbon, a TOC analyzer always requires some accounting for the inorganic carbon (IC) that is always present. TOC analyzers, including a portable TOC analyzer, utilize the same basic technique where acid is added to the liquid sample to remove IC. At this point, the IC is converted into carbon dioxide gas. It is then stripped out of the liquid by a carrier gas where the remaining inorganic carbon-free sample is then oxidized and the carbon dioxide generated from the oxidation process is directly related to the TOC total organic carbon in the sample. There are several methods for introducing the sample to TOC analyzers, including using a syringe, autosampler, and loop sampling. An important specification for total organic carbon analyzers is the measuring range. Carrier gas flow rate, average analysis time and process temperature are important as well for total organic carbon analysis.

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CompanyAnalytik JenaAnalytik JenaAnalytik JenaAnalytik Jena
Itemmulti N/C pharmamulti EA® 4000 for Macro-Elemental Analysismulti N/C 3300multi X® 2500 AOX/TOX Analyzer
Citations
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Catalog Numbermulti EA 4000multi X 2500
Price
Measurement Mode(s)TOC, NPOC, TC, TIC; optional TNb (chemiluminescence, CLD) for combustion models; multi N/C 2100S pharma: TN only for total protein determinationTC, TOC, TIC, EC and BOCTC, TIC, TOC, DOC, NPOC, NPOCplus; optional TNb (CLD or ChD); optional POC (particulate organic carbon)Microcoulometry, NDIR, for AOX, EOX, POX, TOC, TX/TOX
Oxidation Methodpharma UV: UV wet chemical digestion (254 nm + 185 nm, High Power Long Life UV reactor); pharma HT and 3100 pharma: thermocatalytic high-temperature combustion up to 950°CHigh-temperature combustionCatalytic high-temperature combustion up to 950°C (liquids); catalyst-free oxidation up to 1300°C (solids, duo models)Combustion
Measuring Rangepharma UV: 1 µg/L – 10,000 mg/L C; 3100 pharma: 4 µg/L – 30,000 mg/L C; 2100S pharma: 5 µg/L – 200 mg/L TN0 – 100 % C at 0.5 g sample or 500 mg C absolute
0 – 20 % S at 75 mg sample or 15 mg S absolute
0 – 10 % Cl at 100 mg sample or 10 mg Cl absolute		0–30,000 mg/L C; TNb: 0–200 mg/L (CLD) or 0–100 mg/L (ChD); Solids: 0–100 wt-%AOX/ EOX/ POX/ TX/ TOX determination - up to 1,000 µg Cl absolute
TOC determination - up to 10,000 mg/l TOC
Detection Limitpharma UV: 1 µg/L C (ultra-trace without persulfate); pharma HT: 4 µg/L C; 3100 pharma: 4 µg/L C; 2100S pharma: 5 µg/L TNCarbon - 3 ppm at 3 g sample weight or 10 µg C abs | Sulfur - 3 ppm at 3 g sample weight or 10 µg S abs. | Chlorine - 0.3 ppm at 3 g sample weight or 1 µg Cl abs.4 µg/L C; TNb (CLD): 5 µg/L; TNb (ChD): 50 µg/LAOX/ EOX/ POX/ TX/ TOX determination - 10 ng Cl absolute
TOC determination - 0.2 mg/l
Sample Volumepharma UV: up to 20 mL (flow injection); pharma HT: up to 3 mL (flow injection); 3100 pharma: up to 1 mL (ceramic valve, flow injection); 2100S pharma: 50–500 µL (direct syringe injection)Inquire50–1000 µL (standard); 50–3000 µL (3300 HS model)max. 100 µl for EOX extracts and TX for liquid samples max. 100 mg for TX in solid samples.
TOC determination max. 500 µl of the water sample
Measurement AccuracyInquireInquireRSD 1–2%Inquire
Measuring TimeInquireC/S determination (simultaneous or separate): at least 3 minutes, Cl determination: 3 - 10 minutes3–5 min/sampleAOX/EOX/TX: approx. 8 - 10 min depending on concentration and application
TOC: approx. 3 - 5 min depending on concentration and application
DescriptionInquireThe multi EA® 4000 offers precise and reliable environmental analysis and is incredibly easy to use. It guarantees you the fully automated determination of the environmentally relevant parameters TC, TOC, TIC, EC and BOC in soil, sediments, waste, minerals and other inorganic solids.

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... Read More		InquireIn environmental monitoring as well as in process and quality control, the determination of organic halogens which can be adsorbed by activated charcoal is very important for the evaluation of water and waste water. With the multi X® 2500, Analytik Jena provides a flexible, future-oriented system ... Read More
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