Total Organic Carbon Analyzer (TOC Analyzers)

A total organic carbon analyzer (also referred to as TOC analyzers) measures the amount of total organic carbon present in a liquid or water sample. TOC detection is important because of the effects that TOCs may have on health, not to mention the environmental effects and implications for the pharmaceutical manufacturing processes. Since all total organic carbon analyzers only measure total carbon, a TOC analyzer always requires some accounting for the inorganic carbon (IC) that is always present. TOC analyzers, including a portable TOC analyzer, utilize the same basic technique where acid is added to the liquid sample to remove IC. At this point, the IC is converted into carbon dioxide gas. It is then stripped out of the liquid by a carrier gas where the remaining inorganic carbon-free sample is then oxidized and the carbon dioxide generated from the oxidation process is directly related to the TOC total organic carbon in the sample. There are several methods for introducing the sample to TOC analyzers, including using a syringe, autosampler, and loop sampling. An important specification for total organic carbon analyzers is the measuring range. Carrier gas flow rate, average analysis time and process temperature are important as well for total organic carbon analysis.

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CompanyAnalytik JenaAnalytik JenaAnalytik JenaAnalytik Jena
Itemmulti N/C pharmamulti N/C 3300multi N/C® Series TOC/TNb Analyzersmulti X® 2500 AOX/TOX Analyzer
Citations
(758)
(2)
Catalog Numbermulti N/C Seriesmulti X 2500
Price
Measurement Mode(s)TOC, NPOC, TC, TIC; optional TNb (chemiluminescence, CLD) for combustion models; multi N/C 2100S pharma: TN only for total protein determinationTC, TIC, TOC, DOC, NPOC, NPOCplus; optional TNb (CLD or ChD); optional POC (particulate organic carbon)TC, TIC, TOC, NPOC, POC, and TNbMicrocoulometry, NDIR, for AOX, EOX, POX, TOC, TX/TOX
Oxidation Methodpharma UV: UV wet chemical digestion (254 nm + 185 nm, High Power Long Life UV reactor); pharma HT and 3100 pharma: thermocatalytic high-temperature combustion up to 950°CCatalytic high-temperature combustion up to 950°C (liquids); catalyst-free oxidation up to 1300°C (solids, duo models)High temperature combustion / Wet chemical oxidation by UV radiation (254 nm+185 nm) /persulfate dependent on instrument configurationCombustion
Measuring Rangepharma UV: 1 µg/L – 10,000 mg/L C; 3100 pharma: 4 µg/L – 30,000 mg/L C; 2100S pharma: 5 µg/L – 200 mg/L TN0–30,000 mg/L C; TNb: 0–200 mg/L (CLD) or 0–100 mg/L (ChD); Solids: 0–100 wt-%0–30,000 mg/L CAOX/ EOX/ POX/ TX/ TOX determination - up to 1,000 µg Cl absolute
TOC determination - up to 10,000 mg/l TOC
Detection Limitpharma UV: 1 µg/L C (ultra-trace without persulfate); pharma HT: 4 µg/L C; 3100 pharma: 4 µg/L C; 2100S pharma: 5 µg/L TN4 µg/L C; TNb (CLD): 5 µg/L; TNb (ChD): 50 µg/L1 µg/L C - 50 µg/L C dependent on instrument configurationAOX/ EOX/ POX/ TX/ TOX determination - 10 ng Cl absolute
TOC determination - 0.2 mg/l
Sample Volumepharma UV: up to 20 mL (flow injection); pharma HT: up to 3 mL (flow injection); 3100 pharma: up to 1 mL (ceramic valve, flow injection); 2100S pharma: 50–500 µL (direct syringe injection)50–1000 µL (standard); 50–3000 µL (3300 HS model)50–20,000 µL variable dependent on instrument configurationmax. 100 µl for EOX extracts and TX for liquid samples max. 100 mg for TX in solid samples.
TOC determination max. 500 µl of the water sample
Measurement AccuracyInquireRSD 1–2%InquireInquire
Measuring TimeInquire3–5 min/sampleApprox. 3–5 min for each parameterAOX/EOX/TX: approx. 8 - 10 min depending on concentration and application
TOC: approx. 3 - 5 min depending on concentration and application
DescriptionInquireInquiremulti N/C Series Robust and reliable for any TOC/TNbapplication
  • Reliable analysis of TC, TIC, TOC, NPOC, POC, and TNb
  • Guaranteed compliance with standards (e.g. DIN 1484, 15936, 12260...)
  • Accurate results even with complicated matrices
New High-performance TOC/TNb Analysis tailored for the ... Read More		In environmental monitoring as well as in process and quality control, the determination of organic halogens which can be adsorbed by activated charcoal is very important for the evaluation of water and waste water. With the multi X® 2500, Analytik Jena provides a flexible, future-oriented system ... Read More
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