A total organic carbon analyzer (also referred to as TOC analyzers) measures the amount of total organic carbon present in a liquid or water sample. TOC detection is important because of the effects that TOCs may have on health, not to mention the environmental effects and implications for the pharmaceutical manufacturing processes. Since all total organic carbon analyzers only measure total carbon, a TOC analyzer always requires some accounting for the inorganic carbon (IC) that is always present.
TOC analyzers, including a portable TOC analyzer, utilize the same basic technique where acid is added to the liquid sample to remove IC. At this point, the IC is converted into carbon dioxide gas. It is then stripped out of the liquid by a carrier gas where the remaining inorganic carbon-free sample is then oxidized and the carbon dioxide generated from the oxidation process is directly related to the TOC total organic carbon in the sample. There are several methods for introducing the sample to TOC analyzers, including using a syringe, autosampler, and loop sampling. An important specification for total organic carbon analyzers is the measuring range. Carrier gas flow rate, average analysis time and process temperature are important as well for total organic carbon analysis.
Find, compare, and request a quote for total organic carbon analyzers (TOC analyzers) across leading suppliers at Labcompare; including access to product citations, related published figures, and first-hand reviews from our scientific community.
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| Company | Analytik Jena | Analytik Jena | Analytik Jena | Analytik Jena |
| Item | multi N/C pharma | multi N/C 3300 | multi N/C 4300 UV | multi X® 2500 AOX/TOX Analyzer |
| Citations | | | | |
| Catalog Number | | | | multi X 2500 |
| Price | | | | |
| Measurement Mode(s) | TOC, NPOC, TC, TIC; optional TNb (chemiluminescence, CLD) for combustion models; multi N/C 2100S pharma: TN only for total protein determination | TC, TIC, TOC, DOC, NPOC, NPOCplus; optional TNb (CLD or ChD); optional POC (particulate organic carbon) | TC, TIC, TOC, DOC, NPOC, NPOCplus; optional solids TC/TOC/TIC (no TNb) | Microcoulometry, NDIR, for AOX, EOX, POX, TOC, TX/TOX |
| Oxidation Method | pharma UV: UV wet chemical digestion (254 nm + 185 nm, High Power Long Life UV reactor); pharma HT and 3100 pharma: thermocatalytic high-temperature combustion up to 950°C | Catalytic high-temperature combustion up to 950°C (liquids); catalyst-free oxidation up to 1300°C (solids, duo models) | UV wet chemical digestion (high-power UV reactor, 254 nm and 185 nm wavelengths); optional non-catalytic high-temperature combustion up to 1300°C for solids (HT 1300 module) | Combustion |
| Measuring Range | pharma UV: 1 µg/L – 10,000 mg/L C; 3100 pharma: 4 µg/L – 30,000 mg/L C; 2100S pharma: 5 µg/L – 200 mg/L TN | 0–30,000 mg/L C; TNb: 0–200 mg/L (CLD) or 0–100 mg/L (ChD); Solids: 0–100 wt-% | 0–10,000 mg/L C | AOX/ EOX/ POX/ TX/ TOX determination - up to 1,000 µg Cl absolute
TOC determination - up to 10,000 mg/l TOC |
| Detection Limit | pharma UV: 1 µg/L C (ultra-trace without persulfate); pharma HT: 4 µg/L C; 3100 pharma: 4 µg/L C; 2100S pharma: 5 µg/L TN | 4 µg/L C; TNb (CLD): 5 µg/L; TNb (ChD): 50 µg/L | 1 µg/L C | AOX/ EOX/ POX/ TX/ TOX determination - 10 ng Cl absolute
TOC determination - 0.2 mg/l |
| Sample Volume | pharma UV: up to 20 mL (flow injection); pharma HT: up to 3 mL (flow injection); 3100 pharma: up to 1 mL (ceramic valve, flow injection); 2100S pharma: 50–500 µL (direct syringe injection) | 50–1000 µL (standard); 50–3000 µL (3300 HS model) | 50–20,000 µL (flow injection) | max. 100 µl for EOX extracts and TX for liquid samples max. 100 mg for TX in solid samples.
TOC determination max. 500 µl of the water sample |
| Measurement Accuracy | Inquire | RSD 1–2% | 1–2% | Inquire |
| Measuring Time | Inquire | 3–5 min/sample | 3–5 min/sample | AOX/EOX/TX: approx. 8 - 10 min depending on concentration and application
TOC: approx. 3 - 5 min depending on concentration and application |
| Description | Inquire | Inquire | Inquire | In environmental monitoring as well as in process and quality control, the determination of organic halogens which can be adsorbed by activated charcoal is very important for the evaluation of water and waste water. With the multi X® 2500, Analytik Jena provides a flexible, future-oriented system In environmental monitoring as well as in process and quality control, the determination of organic halogens which can be adsorbed by activated charcoal is very important for the evaluation of water and waste water. With the multi X® 2500, Analytik Jena provides a flexible, future-oriented system for sum parameter analysis that meets the requirements of every modern laboratory.
Features:- Very easy handling
- Plug-and-start technology
- Significantly reduced maintenance work
- Intelligent software package multiWin®
- Fast changeover between batch and column method
- User-friendly design ensures outstanding ease of use and efficiency
- High sample throughput in the vertical and horizontal mode
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