Isothermal titration calorimetry is an analytical technique that measures heat discharge along a bimolecular reaction. Often used to determine the thermodynamic parameters associated with a binding event, isothermal titration calorimeters (ITC) can analyze binding affinity, stoichiometry, enthalpy change, and numerous other parameters. With uses in biochemistry, pharmaceutical, and other industries, isothermal titration calorimeters are an essential instrument while studying molecular interactions. Isothermal titration calorimeters offer excellent long-term temperature stability while providing more automation to increase laboratory throughput while reducing the need for analysts' time. When comparing different models of ITC be sure to consider the sensitivity, accuracy, and temperature control systems to allow for fine-tuning of sample analysis.
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| Company | TA Instruments | TA Instruments | TA Instruments | TA Instruments | TA Instruments |
| Item | TAM Air Isothermal Calorimeters | Affinity Isothermal Titration Calorimeter | Nano Isothermal Titration Calorimeter | TAM IV Isothermal Calorimeters | TAM IV-48 Isothermal Calorimeters |
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| Catalog Number | TAM | | | TAM IV | TAM IV-48 |
| Price | | | | | |
| Temperature Range | 5 to 90 ºC | 2 to 80°C | 2 to 80°C | 4 to 150 °C | 4 to 150 °C |
| Description | The TAM Air from TA Instruments is a powerful isothermal calorimeter with heat flow sensitivity in the microwatt range and unmatched baseline drift performance.
Features:
- Operating temperature range: 5 °C to 90 °C
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· Circulating air thermostat with temperature stability at ± 0.001 °C
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The TAM Air from TA Instruments is a powerful isothermal calorimeter with heat flow sensitivity in the microwatt range and unmatched baseline drift performance.
Features:
- Operating temperature range: 5 °C to 90 °C
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· Circulating air thermostat with temperature stability at ± 0.001 °C
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Updated electronics for accurate data acquisition and EU ROHS compliance
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User choice of 8-channel or 3-channel calorimeter configuration
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Improved baseline drift performance for long term (e.g. weeks) experiments
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Connect up to 8 external probes including I/O Voltage card
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Compatible with all current TAM Air ampoules
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Operates with complete TAM IV Lab Asst. software
... Read More | The Affinity ITC and ITC Auto are designed for the most challenging life science laboratory environments that require high sensitivity, high productivity and the most advanced ITC technologies. The Affinity ITC brings advanced engineering to all critical aspects of the measurement ensuring the The Affinity ITC and ITC Auto are designed for the most challenging life science laboratory environments that require high sensitivity, high productivity and the most advanced ITC technologies. The Affinity ITC brings advanced engineering to all critical aspects of the measurement ensuring the highest quality ITC data.... Read More | The Nano ITC Standard Volume and Nano ITC Low Volume isothermal titration calorimeters are designed to provide maximum sensitivity and flexibility for the study of biomolecular binding. Both instruments use solid state thermoelectric heating and cooling systems to precisely control temperature, and The Nano ITC Standard Volume and Nano ITC Low Volume isothermal titration calorimeters are designed to provide maximum sensitivity and flexibility for the study of biomolecular binding. Both instruments use solid state thermoelectric heating and cooling systems to precisely control temperature, and have the same flexible injection syringe assemblies for efficient and accurate delivery of titrant. The true isothermal power compensation design of the Nano ITC instruments provides the highest sensitivity and flexibility for an ultrasensitive ITC analyzing biological samples in-solution.... Read More | TAM IV is the most sensitive, stable and flexible microcalorimeter system in the world for directly measuring this universal heat signal and, therefore, the quantitative thermodynamic and kinetic observation of any process. It is a unique microcalorimeter system that is completely modular and TAM IV is the most sensitive, stable and flexible microcalorimeter system in the world for directly measuring this universal heat signal and, therefore, the quantitative thermodynamic and kinetic observation of any process. It is a unique microcalorimeter system that is completely modular and combines the highest heat flow sensitivity with unmatched long term temperature stability for measuring many processes that are undetectable by other techniques. A wide range of calorimeter configurations and sample handling systems provide maximum application flexibility and ensure optimum laboratory productivity.... Read More | TAM IV-48 is a high-throughput version of the TAM IV and can accommodate up to 48 individual 4 mL Minicalorimeters. The large number of independent and parallel sample-measurements makes this system the optimal solution for sample screening, formulation, and process development. It is equally usefulTAM IV-48 is a high-throughput version of the TAM IV and can accommodate up to 48 individual 4 mL Minicalorimeters. The large number of independent and parallel sample-measurements makes this system the optimal solution for sample screening, formulation, and process development. It is equally useful in research laboratories as in industrial laboratories including pharmaceutical production control.... Read More |
| Temperature Stability | Inquire | 0.00005°C at 25°C | 0.0002°C @ 25°C | Inquire | Inquire |
| Long Term Stability | Inquire | Inquire | Inquire | less than ± 100 µ °C/24h | < ± 100 µ°c/24h ±="" 100=""> |
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