| Description | Couple the miniDAWN™ to your favorite HPLC or FPLC to determine the absolute molar masses and sizes of macromolecules and nanoparticles in solution from hundreds to millions of Daltons—without the need for column calibration standards. This sensitive unit requires as little as 25 ng injected Couple the miniDAWN™ to your favorite HPLC or FPLC to determine the absolute molar masses and sizes of macromolecules and nanoparticles in solution from hundreds to millions of Daltons—without the need for column calibration standards. This sensitive unit requires as little as 25 ng injected sample, 100 kDa polystyrene in THF (varies for other samples and solvents). The miniDAWN is engineered with self-contained modules that are easily replaced making it field serviceable. The system-ready monitors soise levels in real-time and an all-green status indicator lets you know when your system is ready for data collection. The optional DLS module uses the WyattQELS™ module, which fits inside the miniDAWN to providing on-line dynamic light scattering for determining radii down to 0.5 nm. All light scattering cells are subject to contamination by particles and to combat this issue the instrument has a self-cleaning, embedded COMET™ ultrasonic module. For maximum reliability and uptime, program the miniDAWN to automatically clean the cell after every run. The units may also be combined with a Calypso™ composition-gradient system to characterize biomolecular interactions.... Read More | Fast, decisive, low-volume particle characterization analysis for biotherapeutic workflows
When you need the flexibility to conduct particle characterization analyses on different types of biologics, including protein and antibody therapeutics, cell therapies, and gene therapies, the Aura+ System Fast, decisive, low-volume particle characterization analysis for biotherapeutic workflows
When you need the flexibility to conduct particle characterization analyses on different types of biologics, including protein and antibody therapeutics, cell therapies, and gene therapies, the Aura+ System has you covered.
Fully configured to support applications across protein, antibody, cell, and gene therapy workflows, Aura+ brings particle characterization to earlier stages of therapeutic development, so you can make better decisions sooner.
Powered by the backgrounded membrane imaging (BMI) and fluorescence membrane microscopy (FMM) technology shared within the Aura family of instruments, Aura+ System enables applications from late discovery to development and manufacturing, enhancing decision-making and accelerating your success.
Features:- Save precious material with just 5 µL sample volume requirements
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Get actionable results from a full 96 well plate of labeled samples to data in just 90 minutes
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Boost efficiency with 96-well membrane plate high-throughput capability
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Gain deeper particle insights with advanced imaging
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Rely only on one platform for proteins, antibodies, and cell and gene therapies development
... Read More | Delivering up to 4× faster runs with half the sample, the omniDAWN™ multi-angle static light scattering (MALS) photometer is purpose-built for UPLC™ and UHPLC systems for non-destructive absolute molar mass and size characterization of macromolecules and nanoparticles in solution. It provides Delivering up to 4× faster runs with half the sample, the omniDAWN™ multi-angle static light scattering (MALS) photometer is purpose-built for UPLC™ and UHPLC systems for non-destructive absolute molar mass and size characterization of macromolecules and nanoparticles in solution. It provides exceptional sensitivity across a broad range of molecular weights, sizes, and concentrations, supported by advanced analysis modules, practical implementation guides, and intelligent system health monitoring to ensure reliable performance and streamlined workflows.... Read More |
| Applications | With SEC/GPC: determination of distributions of absolute molar mass, size, conformation, conjugate ratio. With Calypso CG-MALS: characterization of biomolecular interactions. | Inquire | With standard SEC/GPC or EclipseTM (FFF system): determination of distributions of molar mass, size, conformation, conjugation ratio, and particle concentration. With the Calypso composition-gradient system: label-free characterization of biomolecular interactions, including self- and hetero-association as well as non-specific interactions. |