| Description | Fast, decisive, low-volume particle characterization analysis for biotherapeutic workflows
When you need the flexibility to conduct particle characterization analyses on different types of biologics, including protein and antibody therapeutics, cell therapies, and gene therapies, the Aura+ System Fast, decisive, low-volume particle characterization analysis for biotherapeutic workflows
When you need the flexibility to conduct particle characterization analyses on different types of biologics, including protein and antibody therapeutics, cell therapies, and gene therapies, the Aura+ System has you covered.
Fully configured to support applications across protein, antibody, cell, and gene therapy workflows, Aura+ brings particle characterization to earlier stages of therapeutic development, so you can make better decisions sooner.
Powered by the backgrounded membrane imaging (BMI) and fluorescence membrane microscopy (FMM) technology shared within the Aura family of instruments, Aura+ System enables applications from late discovery to development and manufacturing, enhancing decision-making and accelerating your success.
Features:- Save precious material with just 5 µL sample volume requirements
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Get actionable results from a full 96 well plate of labeled samples to data in just 90 minutes
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Boost efficiency with 96-well membrane plate high-throughput capability
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Gain deeper particle insights with advanced imaging
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Rely only on one platform for proteins, antibodies, and cell and gene therapies development
... Read More | Accelerate protein formulation development and screening for therapeutic drug development
Protein stability analysis and preventing aggregation are is crucial when developing therapies. That’s why it’s time to leave flow cell imaging behind.
Speed up protein formulation development and screening Accelerate protein formulation development and screening for therapeutic drug development
Protein stability analysis and preventing aggregation are is crucial when developing therapies. That’s why it’s time to leave flow cell imaging behind.
Speed up protein formulation development and screening with Aura PTx. With just 5 µL of a sample, discover a faster way to detect, count and characterize excipients and drug products at earlier stages of therapeutic development.
Now you can quickly identify and count aggregates that form due to degraded polysorbate in your formulation. And with two-channel fluorescence, determine if aggregation in your protein therapy is caused by proteins or polysorbates in your sample – at the same time.
Features:- Learn more with innovative technology. Aura PTx System combines backgrounded membrane imaging (BMI) with two channels of fluorescence membrane microscopy (FMM) to give you protein aggregate data without the need to clean between measurements.
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ID protein aggregates. Accurately detect excipient degradation within your formulations and distinguish between protein and non-protein particles effortlessly.
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Monitor polysorbate degradation. With fluorescence applications, you can track polysorbate degradation to confidently evaluate the stability of your product.
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Analyze small volumes. You only need 5 µL of sample, allowing you to start characterizing protein aggregates earlier in development.
... Read More | The DAWN™ instrument is an advanced detector for precise characterization of proteins, polymers, and nanoparticles including viral vectors, lipid nanoparticles and vesicles. Using multi-angle static light scattering (MALS) and optional dynamic light scattering (DLS), DAWN analyzes molar massThe DAWN™ instrument is an advanced detector for precise characterization of proteins, polymers, and nanoparticles including viral vectors, lipid nanoparticles and vesicles. Using multi-angle static light scattering (MALS) and optional dynamic light scattering (DLS), DAWN analyzes molar mass, size, conformation, particle concentration, conjugation (e.g. glycoproteins) or encapsulation (e.g. AAV capsid content). It stands out with exceptional sensitivity and the widest range of molecular weight, size, and concentration of any MALS instrument, paired with a broad selection of configurations and optional modules for enhanced capabilities.
The DAWN is most often used in conjunction with gel permeation chromatography (GPC-MALS), size exclusion chromatography (SEC-MALS) or an EclipseTM, field-flow fractionation instrument (FFF-MALS) and may also be used with ion-exchange chromatography or reverse-phase chromatography. The instrument includes a high-resolution, touch-screen front panel to display data graphs, system health and instrument diagnostics and is accompanied by ASTRA™, the most versatile software package available for analysis of online multi-angle and dynamic light scattering.... Read More |