| Description | Accelerate protein formulation development and screening for therapeutic drug development
Protein stability analysis and preventing aggregation are is crucial when developing therapies. That’s why it’s time to leave flow cell imaging behind.
Speed up protein formulation development and screening Accelerate protein formulation development and screening for therapeutic drug development
Protein stability analysis and preventing aggregation are is crucial when developing therapies. That’s why it’s time to leave flow cell imaging behind.
Speed up protein formulation development and screening with Aura PTx. With just 5 µL of a sample, discover a faster way to detect, count and characterize excipients and drug products at earlier stages of therapeutic development.
Now you can quickly identify and count aggregates that form due to degraded polysorbate in your formulation. And with two-channel fluorescence, determine if aggregation in your protein therapy is caused by proteins or polysorbates in your sample – at the same time.
Features:- Learn more with innovative technology. Aura PTx System combines backgrounded membrane imaging (BMI) with two channels of fluorescence membrane microscopy (FMM) to give you protein aggregate data without the need to clean between measurements.
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ID protein aggregates. Accurately detect excipient degradation within your formulations and distinguish between protein and non-protein particles effortlessly.
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Monitor polysorbate degradation. With fluorescence applications, you can track polysorbate degradation to confidently evaluate the stability of your product.
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Analyze small volumes. You only need 5 µL of sample, allowing you to start characterizing protein aggregates earlier in development.
... Read More | Fast, decisive, low-volume particle characterization analysis for biotherapeutic workflows
When you need the flexibility to conduct particle characterization analyses on different types of biologics, including protein and antibody therapeutics, cell therapies, and gene therapies, the Aura+ System Fast, decisive, low-volume particle characterization analysis for biotherapeutic workflows
When you need the flexibility to conduct particle characterization analyses on different types of biologics, including protein and antibody therapeutics, cell therapies, and gene therapies, the Aura+ System has you covered.
Fully configured to support applications across protein, antibody, cell, and gene therapy workflows, Aura+ brings particle characterization to earlier stages of therapeutic development, so you can make better decisions sooner.
Powered by the backgrounded membrane imaging (BMI) and fluorescence membrane microscopy (FMM) technology shared within the Aura family of instruments, Aura+ System enables applications from late discovery to development and manufacturing, enhancing decision-making and accelerating your success.
Features:- Save precious material with just 5 µL sample volume requirements
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Get actionable results from a full 96 well plate of labeled samples to data in just 90 minutes
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Boost efficiency with 96-well membrane plate high-throughput capability
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Gain deeper particle insights with advanced imaging
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Rely only on one platform for proteins, antibodies, and cell and gene therapies development
... Read More | Unique among its peers, the DynaPro™ Zetastar™ performs simultaneous dynamic and static light scattering or dynamic and electrophoretic light scattering (DLS/SLS/ELS) measurements all within one instrument. Automate measurements of zeta potential and size for up to 96 samples at a time Unique among its peers, the DynaPro™ Zetastar™ performs simultaneous dynamic and static light scattering or dynamic and electrophoretic light scattering (DLS/SLS/ELS) measurements all within one instrument. Automate measurements of zeta potential and size for up to 96 samples at a time or measure manually with cuvettes with the walk-up touch screen functionality for optimal efficiency. Quickly quantify size, polydispersity, zeta potential/charge, particle concentration, molar mass or turbidity for characterization and stability studies.
Key Features:
- DYNAMICS™ Touch on-board app for walk-up, self-guided operation
- Pairable with a Waters HPLC and Pump to automate measurements of zeta potential and size
- Flow Mode for best-in-class zeta potential reproducibility and precision for samples in high salt buffers or prone to degradation
- Adaptive collection for faster and simpler measurements of zeta potential
- Measure size and turbidity with just 2 µL of solution, or zeta potential with as little as 65 µL of solution
- A selection of high-quality quartz and disposable cells and cuvettes for both size and zeta potential measurements
... Read More |
| Applications | Inquire | Inquire | Analysis of proteins, gene vectors, viruses and virus-like particles, promiscuous inhibitors, micelles, nano-emulsions, lipid and metallic nanoparticles, and more. |