| Description | Fast, decisive, low-volume AAV characterization for gene therapy development workflows
Adeno-associated viruses (AAVs) have revolutionized gene therapy product development. With limited material available, allocating valuable samples for aggregate testing may have seemed impractical—until now.
AuraFast, decisive, low-volume AAV characterization for gene therapy development workflows
Adeno-associated viruses (AAVs) have revolutionized gene therapy product development. With limited material available, allocating valuable samples for aggregate testing may have seemed impractical—until now.
Aura GT System is the first and only system designed to detect, count, and characterize AAV particles with just 5 µL. Combining backgrounded membrane imaging (BMI) with fluorescence membrane microscopy (FMM) dual-channel technology, confident decisions can be made earlier—one step closer to success.
Analyze small volumes. Only 5 µL of sample is needed, allowing particle characterization in early phase development.
Characterize and identify viral vectors. Aura GT System distinguishes between capsid and non-capsid aggregates and enables you to confirm whether DNA leakage is the root cause of aggregation straight from the box.
Gain deeper gene therapy understanding. Gain insight with Aura GT System’s duo of BMI and FMM, which distinguish and characterize different serotypes for aggregation and product features for deeper understanding of gene therapy – without tedious, labor-intensive assays.
Features:- Characterize AAV, lentivirus, and other viral vectors across key applications like aggregation and stability.
-
Detect, count, and characterize AAV particles with just 5 µL of sample. Identify capsid and DNA aggregates in your gene therapy sample with confidence.
-
Make direct comparisons between different formulations, AAV serotypes, storage conditions, and lots.
-
Detect and count particles from 1 µm up to 5 mm.
-
Save time with measurements under one minute per sample.
... Read More | Accurately identify, count, and characterize subvisible particle contaminants in minutes with Aura CL
Measuring particles in cell therapy manufacturing has always been a challenge, and the fact that the drug product itself is a particle makes it even harder.
Waters Aura CL System is the first Accurately identify, count, and characterize subvisible particle contaminants in minutes with Aura CL
Measuring particles in cell therapy manufacturing has always been a challenge, and the fact that the drug product itself is a particle makes it even harder.
Waters Aura CL System is the first system that, unlike traditional methods, quickly identifies and distinguishes cells from protein aggregates or harm-causing particles while providing all required cytometric capabilities—counting cells, identifying types, and measuring viability in one simple assay.
Powered by innovative technology, Waters Aura CL System is the ultimate tool to identify, count, and characterize subvisible particle contaminants introduced in cell therapy manufacturing—so you can access high-throughput insights earlier in discovery to develop cell therapies faster, smarter, and safer.
Features:- Detect and count residual Dynabeads. Finding and counting Dynabeads™* is easier than ever with Aura CL System. Unlike traditional methods that can be subjective, cumbersome, inaccurate, and prone to error, this powerful, fully automated tool allows you to make an accurate count at high speed.
-
ID cells/non cells. Rather than spending hours manually sorting through images or learning how to use complex machine learning libraries, Aura CL System makes it easy to precisely ID cells from non-cell aggregates right out of the box.
-
Analyze small volumes. Analyze small volumes. You only need 5 µL of sample, which allows for particle and cell characterization earlier in development.
-
Learn more with innovative technology. Using backgrounded membrane imaging (BMI) and fluorescence membrane microscopy (FMM), Aura CL System performs cell viability assays with definitive cell identification for 96 40-µL samples in under an hour.
... Read More | Fast, decisive, low-volume particle characterization analysis for biotherapeutic workflows
When you need the flexibility to conduct particle characterization analyses on different types of biologics, including protein and antibody therapeutics, cell therapies, and gene therapies, the Aura+ System Fast, decisive, low-volume particle characterization analysis for biotherapeutic workflows
When you need the flexibility to conduct particle characterization analyses on different types of biologics, including protein and antibody therapeutics, cell therapies, and gene therapies, the Aura+ System has you covered.
Fully configured to support applications across protein, antibody, cell, and gene therapy workflows, Aura+ brings particle characterization to earlier stages of therapeutic development, so you can make better decisions sooner.
Powered by the backgrounded membrane imaging (BMI) and fluorescence membrane microscopy (FMM) technology shared within the Aura family of instruments, Aura+ System enables applications from late discovery to development and manufacturing, enhancing decision-making and accelerating your success.
Features:- Save precious material with just 5 µL sample volume requirements
-
Get actionable results from a full 96 well plate of labeled samples to data in just 90 minutes
-
Boost efficiency with 96-well membrane plate high-throughput capability
-
Gain deeper particle insights with advanced imaging
-
Rely only on one platform for proteins, antibodies, and cell and gene therapies development
... Read More |