| Description | The analysis of amino acids plays an important role not only in the food industry, but also in natural product and pharmaceutical fields. This system uses detection by post-column fluorescence derivatization, with o-phthalaldehyde (OPA) / N-acetylcysteine as the reaction reagent, to selectively and The analysis of amino acids plays an important role not only in the food industry, but also in natural product and pharmaceutical fields. This system uses detection by post-column fluorescence derivatization, with o-phthalaldehyde (OPA) / N-acetylcysteine as the reaction reagent, to selectively and with high sensitivity quantitate the amino acids contained in samples with high levels of contaminants.
Features - Selectively detects amino acids based on Shimadzu's highly acclaimed post-column reaction technology and high-sensitivity fluorescence detector.
Detects amino acids with over ten times higher sensitivity than the ninhydrin method (UV detection), by using a derivatization method that provides selective reaction with amino radicals, together with fluorescence detection. - Outstanding Reproducibility
Because derivatization occurs after separation in the column, reactions are not affected by the sample matrix. Therefore, analyses can be performed with good precision. - Easy to Operate
Since column eluant is automatically derivatized by mixing it with the reaction reagent, it saves time and tedious tasks. - The mobile phase and reaction solution are available as a kit, which means solutions can be prepared with minimal fuss.
... Read More | Automatically and seamlessly conducting all processes from sample pre-treatment to analysis, the Prominence 2D HPLC for BA is a column-switching HPLC system equipped with the newly developed Shim-pack MAYI-ODS pretreatment column and a unique on-line dilution bypass channel. The system’s on-line preAutomatically and seamlessly conducting all processes from sample pre-treatment to analysis, the Prominence 2D HPLC for BA is a column-switching HPLC system equipped with the newly developed Shim-pack MAYI-ODS pretreatment column and a unique on-line dilution bypass channel. The system’s on-line pre-treatment of bio-samples reduces labor while enhancing efficiency. A high-throughput autosampler provides high-speed injection and reproducibility. Accurate and precise temperature control of the system further ensures reproducible analysis and a high recovery rate. Key features include: - Shim-pack MAYI-ODS Pretreatment Column – This unique column effectively removes proteins from bio-samples, achieves long-term stability through optimization of particle diameter and newly developed coating technology, and exhibits excellent repeatability
- On-line Dilution Bypass Effect – Eliminates the need for preliminary dilution of the sample by automatically diluting it on-line, leading to excellent recovery rates
- Suppression of Carryover – A number of enhancements, including a specially treated outer needle surface and improvement of needle seal composition, greatly reduce sample adsorption, critical for achieving the high sensitivity of LC-MS/MS
- Precise Temperature Control of the Pretreatment Column
This system serves as a front-end HPLC system for a mass spectrometer, enhancing the efficiency of analyzing drugs in bio-samples in pharmacokinetics studies and clinical tests. ... Read More |