| Description | Automatically and seamlessly conducting all processes from sample pre-treatment to analysis, the Prominence 2D HPLC for BA is a column-switching HPLC system equipped with the newly developed Shim-pack MAYI-ODS pretreatment column and a unique on-line dilution bypass channel. The system’s on-line preAutomatically and seamlessly conducting all processes from sample pre-treatment to analysis, the Prominence 2D HPLC for BA is a column-switching HPLC system equipped with the newly developed Shim-pack MAYI-ODS pretreatment column and a unique on-line dilution bypass channel. The system’s on-line pre-treatment of bio-samples reduces labor while enhancing efficiency. A high-throughput autosampler provides high-speed injection and reproducibility. Accurate and precise temperature control of the system further ensures reproducible analysis and a high recovery rate. Key features include: - Shim-pack MAYI-ODS Pretreatment Column – This unique column effectively removes proteins from bio-samples, achieves long-term stability through optimization of particle diameter and newly developed coating technology, and exhibits excellent repeatability
- On-line Dilution Bypass Effect – Eliminates the need for preliminary dilution of the sample by automatically diluting it on-line, leading to excellent recovery rates
- Suppression of Carryover – A number of enhancements, including a specially treated outer needle surface and improvement of needle seal composition, greatly reduce sample adsorption, critical for achieving the high sensitivity of LC-MS/MS
- Precise Temperature Control of the Pretreatment Column
This system serves as a front-end HPLC system for a mass spectrometer, enhancing the efficiency of analyzing drugs in bio-samples in pharmacokinetics studies and clinical tests. ... Read More | Built for fast and accurate sample analysis, the latest iteration of Shimadzu’s compact, robust integrated (U)HPLC system maintains the excellent core performance capabilities of its predecessor while incorporating innovative functionality to drive productivity and ensure high-quality analytical Built for fast and accurate sample analysis, the latest iteration of Shimadzu’s compact, robust integrated (U)HPLC system maintains the excellent core performance capabilities of its predecessor while incorporating innovative functionality to drive productivity and ensure high-quality analytical results.
Features include:
- Excellent baseline stability with advanced optical temperature control
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High-capacity oven with precise temperature control
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Ultra-fast 14-second injection cycle achievable
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Outstanding reproducibility and linearity with near zero carryover
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UV or PDA detector standard; optional detectors, including single LCMS, can be added
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Auto validation function
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Optimized method development when combined with LabSolutions MD software
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Easy-to-use, easy-access front-panel interface replicates the system flow channel and simplifies the operating status of the system
The new i-Series incorporates multiple automated functions that simplify workflows and enable higher work efficiency, such as:
- Automated flow rate control
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Mobile phase monitoring
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Automatic detection & correction of air bubbles
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Automated method development
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Automated peak identification
Maintenance reminders, remote operation and monitoring, and a new intelligent column management tool, which tracks column usage and performance, help to maintain analytical robustness and deliver consistent, reliable results for all users.... Read More |