HPLC Instrument

High-performance liquid chromatography (HPLC) (also called high-pressure liquid chromatography) is a solution-phase technique for fractionation of complex samples. Unlike standard column chromatography, HPLC is an active process in which materials are pumped at high pressure through the separation column, which contains the so-called “stationary phase” of the separation in the form of densely packed, often chemically functionalized beads. Once introduced to the column, it is the sample’s differential affinity for the solvent (“mobile”) and stationary phases that enables separation to occur, generally with sharper resolution than standard liquid chromatography. High performance liquid chromatographs can be used for analytical or preparative applications depending on the HPLC pump and the column size. HPLC columns are available in a variety of formats, including reverse phase, ion exchange, and size exclusion, which separate based on polarity, charge, and size, respectively.

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CompanyThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher ScientificThermo Fisher Scientific
ItemVanquish™ Analytical Purification SystemThermo Scientific Vanquish Inverse Gradient LC SystemThermo Scientific Vanquish Refractive Index DetectorVanquish™ Flex Quaternary UHPLC SystemVanquish™ High-throughput LC Systems
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Catalog NumberIQLAAAGABHFAPUMZZZIQLAAAGABHFAPUMZZZIQLAAAGABHFAPUMZZZIQLAAAGABHFAPUMBHVIQLAAAGABHFAPUMZZZ
Price
TypeIntegrated (U)HPLC system for anayltical purfication by precise fractionationInquireInquireUHPLCUHPLC
Detector(s)Diode Array DetectorInquireInquireInquireDiode Array Detector
Flow Rateup to 5mL/minInquireInquire8 mL/minup to 5mL/min
Max. Pressure1500 bar (22,000 psi) depending on configurationInquireInquireup to 1000 bar (15,000psi)Up to 1500 bar (22,000 psi)
DescriptionExperience the high-resolution fractionation of the Thermo Scientific™ Vanquish™ Analytical Purification LC Systems featuring the integrated Thermo Scientific™ Vanquish™ Fraction Collector. Achieve efficient purification by combining the separation power of the Thermo™ ... Read MoreOur portfolio of innovative and dependable liquid chromatography (LC) instruments includes analytical HPLC and UHPLC systems to handle any separation challenge from simple to complex samples; application-specific HPLC and UHPLC systems for applications such as 2D-LC and dual LC; and nano-, capillary... Read MoreExperience the ease of using the Thermo Scientific™ Vanquish™ Refractive Index Detector (RID) for routine isocratic analysis of substances that lack UV chromophores, such as carbohydrates, lipids, and polymers. This detector fully integrates with Thermo Scientific™ Vanquish™ analytical LC systems, ... Read MoreThe Thermo Scientific™ Vanquish™ Flex Quaternary system provides state-of-the-art quaternary solvent blending. As a member of the Thermo Scientific Vanquish UHPLC product line, the Vanquish Flex Quaternary system delivers new benchmarks in accuracy, precision, and sensitivity with a state-of-the-art... Read MoreUse the Thermo Scientific™ Vanquish™ High-throughput LC Systems to improve productivity and save bench space. Vanquish Tandem LC systems increase sample throughput and MS utilization for LC-MS applications by eliminating column washing and equilibration steps from method cycle time. Vanquish Duo ... Read More
QuantityEAEAEAEAEA
Capacityvial capacity of 208 samplesInquireInquirevial capacity of 216 samplesvial capacity of 208 samples
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