| Description | The CF3-C8030 Centrifugal Field-Flow Fractionation system has been designed to improve the separation and analysis of nanoparticle drug delivery systems and other complex pharmaceutical and biopharmaceutical formulations. In addition, the system is ideal for materials science applications, The CF3-C8030 Centrifugal Field-Flow Fractionation system has been designed to improve the separation and analysis of nanoparticle drug delivery systems and other complex pharmaceutical and biopharmaceutical formulations. In addition, the system is ideal for materials science applications, particularly electronics and semiconductor manufacturing.
The CF3-C8030 system improves analytical capabilities by separating particles prior to analysis, enabling high-resolution characterization across a broad particle size range. This physical separation of particle populations helps eliminate interference and provides an accurate view of true particle size populations, including those difficult or impossible to resolve using conventional particle measurement methods.
Key features/benefits include:
- Highest Centrifugal Speed on the Market - Centrifugal forces up to 15,900 × g drive significant improvements in resolution and optimize separation performance, allowing users to resolve closely sized particle populations with exceptional clarity
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Widest Range of Particle Sizes - The system is suitable for simultaneous measurement of samples containing a wide-ranging mix of particle dimensions, from very small nanoparticles to much larger micron-sized particles.
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Superior Separation and Analysis of Smaller Particles - Applying a higher centrifugal force makes it possible to analyze smaller particles.
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Flexible Combination with Various Detectors & Techniques - The CF3-C8030 system supports flexible integration with a variety of complementary technologies, including multiple detector types and electron microscopy for detailed examination of fractionated samples. This adaptability enables comprehensive characterization workflows essential for advanced pharmaceutical and materials research.
... Read More | The analysis of amino acids plays an important role not only in the food industry, but also in natural product and pharmaceutical fields. This system uses detection by post-column fluorescence derivatization, with o-phthalaldehyde (OPA) / N-acetylcysteine as the reaction reagent, to selectively and The analysis of amino acids plays an important role not only in the food industry, but also in natural product and pharmaceutical fields. This system uses detection by post-column fluorescence derivatization, with o-phthalaldehyde (OPA) / N-acetylcysteine as the reaction reagent, to selectively and with high sensitivity quantitate the amino acids contained in samples with high levels of contaminants.
Features - Selectively detects amino acids based on Shimadzu's highly acclaimed post-column reaction technology and high-sensitivity fluorescence detector.
Detects amino acids with over ten times higher sensitivity than the ninhydrin method (UV detection), by using a derivatization method that provides selective reaction with amino radicals, together with fluorescence detection. - Outstanding Reproducibility
Because derivatization occurs after separation in the column, reactions are not affected by the sample matrix. Therefore, analyses can be performed with good precision. - Easy to Operate
Since column eluant is automatically derivatized by mixing it with the reaction reagent, it saves time and tedious tasks. - The mobile phase and reaction solution are available as a kit, which means solutions can be prepared with minimal fuss.
... Read More | The Shimadzu Cannabis Analyzer for Potency captures the spirit of an Analyzer – a comprehensive package integrating instrument hardware, software, consumables, and analytical workflow. Includes a certified reference material (CRM) mixture of target compounds. Also includes a service package to coverThe Shimadzu Cannabis Analyzer for Potency captures the spirit of an Analyzer – a comprehensive package integrating instrument hardware, software, consumables, and analytical workflow. Includes a certified reference material (CRM) mixture of target compounds. Also includes a service package to cover preventive maintenance and warranty for three years, plus free technical support for the life of the product. The solution is ready to use after one day of installation and testing, and requires no time-consuming method development on the part of the analyst.
Choice of three proven HPLC methods: - High Throughput HPLC Method Package – Designed for analysis of the 10 most commonly requested cannabinoids in under 8 minutes. This is the original method developed by Shimadzu in collaboration with industry laboratories. (Does not include THCV.)
- High Sensitivity HPLC Method Package – Adds THCV to the target analyte list, with an instrument cycle time of under 10 minutes. The short analysis time produces the sharpest chromatographic peaks for the best overall sensitivity.
- High Resolution HPLC Method Package – Presents full baseline resolution for all 11 compounds and an analysis time under 30 minutes. This method is preferred for research purposes, or when additional compounds must be added to the analysis in response to new state regulatory requirements.
... Read More | Built for fast and accurate sample analysis, the latest iteration of Shimadzu’s compact, robust integrated (U)HPLC system maintains the excellent core performance capabilities of its predecessor while incorporating innovative functionality to drive productivity and ensure high-quality analytical Built for fast and accurate sample analysis, the latest iteration of Shimadzu’s compact, robust integrated (U)HPLC system maintains the excellent core performance capabilities of its predecessor while incorporating innovative functionality to drive productivity and ensure high-quality analytical results.
Features include:
- Excellent baseline stability with advanced optical temperature control
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High-capacity oven with precise temperature control
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Ultra-fast 14-second injection cycle achievable
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Outstanding reproducibility and linearity with near zero carryover
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UV or PDA detector standard; optional detectors, including single LCMS, can be added
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Auto validation function
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Optimized method development when combined with LabSolutions MD software
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Easy-to-use, easy-access front-panel interface replicates the system flow channel and simplifies the operating status of the system
The new i-Series incorporates multiple automated functions that simplify workflows and enable higher work efficiency, such as:
- Automated flow rate control
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Mobile phase monitoring
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Automatic detection & correction of air bubbles
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Automated method development
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Automated peak identification
Maintenance reminders, remote operation and monitoring, and a new intelligent column management tool, which tracks column usage and performance, help to maintain analytical robustness and deliver consistent, reliable results for all users.... Read More | Method scouting is a process where different mobile phases and column stationary phases are evaluated to determine the best set of separation conditions for a particular sample. Manual solvent preparation, column switching, and method programming are time-consuming steps, so the Nexera method Method scouting is a process where different mobile phases and column stationary phases are evaluated to determine the best set of separation conditions for a particular sample. Manual solvent preparation, column switching, and method programming are time-consuming steps, so the Nexera method scouting system was developed to streamline the entire process for more efficient method development.
The system is based around 2 LC-30AD pumps, each with a quaternary valve, which allows the analyst to run binary gradients with 16 different solvent pairs. A high-pressure column selection valve holds from 1 to 6 columns, resulting in up to 96 unique separation conditions per sample. Ultra-high speed conditions can be easily transferred to conventional conditions using a transfer program. In addition, scouting is performed automatically when the mobile phase is switched.
The Nexera Method Scouting Solution software has intuitive, user-friendly screens to set the pump and column valve positions, gradient program steps, and it automatically builds the sequence table in seconds. Method Scouting Solution provides the data required for analysis via a graphical user interface, as well as automated controls conforming to laboratory operations configured in the system settings.
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