| Description | Method scouting is a process where different mobile phases and column stationary phases are evaluated to determine the best set of separation conditions for a particular sample. Manual solvent preparation, column switching, and method programming are time-consuming steps, so the Nexera method Method scouting is a process where different mobile phases and column stationary phases are evaluated to determine the best set of separation conditions for a particular sample. Manual solvent preparation, column switching, and method programming are time-consuming steps, so the Nexera method scouting system was developed to streamline the entire process for more efficient method development.
The system is based around 2 LC-30AD pumps, each with a quaternary valve, which allows the analyst to run binary gradients with 16 different solvent pairs. A high-pressure column selection valve holds from 1 to 6 columns, resulting in up to 96 unique separation conditions per sample. Ultra-high speed conditions can be easily transferred to conventional conditions using a transfer program. In addition, scouting is performed automatically when the mobile phase is switched.
The Nexera Method Scouting Solution software has intuitive, user-friendly screens to set the pump and column valve positions, gradient program steps, and it automatically builds the sequence table in seconds. Method Scouting Solution provides the data required for analysis via a graphical user interface, as well as automated controls conforming to laboratory operations configured in the system settings.
... Read More | The analysis of amino acids plays an important role not only in the food industry, but also in natural product and pharmaceutical fields. This system uses detection by post-column fluorescence derivatization, with o-phthalaldehyde (OPA) / N-acetylcysteine as the reaction reagent, to selectively and The analysis of amino acids plays an important role not only in the food industry, but also in natural product and pharmaceutical fields. This system uses detection by post-column fluorescence derivatization, with o-phthalaldehyde (OPA) / N-acetylcysteine as the reaction reagent, to selectively and with high sensitivity quantitate the amino acids contained in samples with high levels of contaminants.
Features
- Selectively detects amino acids based on Shimadzu's highly acclaimed post-column reaction technology and high-sensitivity fluorescence detector.
Detects amino acids with over ten times higher sensitivity than the ninhydrin method (UV detection), by using a derivatization method that provides selective reaction with amino radicals, together with fluorescence detection.
- Outstanding Reproducibility
Because derivatization occurs after separation in the column, reactions are not affected by the sample matrix. Therefore, analyses can be performed with good precision.
- Easy to Operate
Since column eluant is automatically derivatized by mixing it with the reaction reagent, it saves time and tedious tasks.
- The mobile phase and reaction solution are available as a kit, which means solutions can be prepared with minimal fuss.
... Read More | The Shimadzu Cannabis Analyzer for Potency captures the spirit of an Analyzer – a comprehensive package integrating instrument hardware, software, consumables, and analytical workflow. Includes a certified reference material (CRM) mixture of target compounds. Also includes a service package to coverThe Shimadzu Cannabis Analyzer for Potency captures the spirit of an Analyzer – a comprehensive package integrating instrument hardware, software, consumables, and analytical workflow. Includes a certified reference material (CRM) mixture of target compounds. Also includes a service package to cover preventive maintenance and warranty for three years, plus free technical support for the life of the product. The solution is ready to use after one day of installation and testing, and requires no time-consuming method development on the part of the analyst.
Choice of three proven HPLC methods:
- High Throughput HPLC Method Package – Designed for analysis of the 10 most commonly requested cannabinoids in under 8 minutes. This is the original method developed by Shimadzu in collaboration with industry laboratories. (Does not include THCV.)
- High Sensitivity HPLC Method Package – Adds THCV to the target analyte list, with an instrument cycle time of under 10 minutes. The short analysis time produces the sharpest chromatographic peaks for the best overall sensitivity.
- High Resolution HPLC Method Package – Presents full baseline resolution for all 11 compounds and an analysis time under 30 minutes. This method is preferred for research purposes, or when additional compounds must be added to the analysis in response to new state regulatory requirements.
... Read More | Building on the exceptional performance of previous versions, the integrated i-Series LC-2050/LC-2060 models incorporate Analytical Intelligence functions, enable complete automation from start-up to analysis preparations, and allow remote monitoring and data processing. In addition, the easy-to-useBuilding on the exceptional performance of previous versions, the integrated i-Series LC-2050/LC-2060 models incorporate Analytical Intelligence functions, enable complete automation from start-up to analysis preparations, and allow remote monitoring and data processing. In addition, the easy-to-use, easy-access front-panel interface replicates the system flow channel and simplifies the operating status of the system. Method editing can also be easily performed directly from the same screen. With this intuitive design, even users who are completely new to liquid chromatography can navigate the user interface with minimal training.
Features include:
- 14-second injection cycle to support high-speed multi-analyte processing
- Lowest carryover (<0.0025%) with exceptional reproducibility
- Increased sample capacity – autosampler accommodates over 1,500 samples
- UV or PDA detector standard; optional detectors can be added
- Forced air circulation column oven for (ambient -10) to 90 degrees temperature control
- Dual temperature-controlled optics and flow cell for excellent baseline stability
- Analytical intelligence functions, including real-time mobile phase monitoring, smart flow control, and i-PeakFinder automatic peak integration
- Easy migration of existing methods from either Shimadzu or non-Shimadzu systems
With LabSolutions Direct, analysts can operate instruments remotely and implement pre-configured methods using the web browser of a computer or a smart device. Instrument status and chromatograms can also be monitored remotely for increased efficiency and uptime.
The i-Series LC-2050/LC-2060 models feature increased pressure tolerance to enable use for a wider range of analysis conditions. The upper pressure limit for the LC-2050 is 50MPa (7,000psi), and for the LC-2060 is 70MPa (10,000psi).... Read More | Enables Both HPLC and UHPLC Analysis
The Nexera-i MT is a new addition to the i-Series lineup. It enables both conventional analysis via its high compatibility with existing LC systems and rapid analysis via high-speed methods. In pharmaceutical development, a single integrated system allows Enables Both HPLC and UHPLC Analysis
The Nexera-i MT is a new addition to the i-Series lineup. It enables both conventional analysis via its high compatibility with existing LC systems and rapid analysis via high-speed methods. In pharmaceutical development, a single integrated system allows process synthesis screening analysis for synthetic substances in the UHPLC flow line, and impurity content identification in the HPLC flow line.
Analysis results from LC systems in the same laboratory may differ, even with the same method, due to differences in the volumes of these systems. The Nexera-i MT demonstrates outstanding reproducibility between various LC systems with different system volumes, simplifying method transfer between instruments.
Further more, with the Nexera-i MT the process of migrating from UHPLC to HPLC or from HPLC to UHPLC can be accomplished using a single system. The Nexera-i MT is based on the same user-friendly i-Series, but maximizes performance and reliability for migrating and transferring customer methods.... Read More |