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| Company | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation |
| Item | MRL-248 | 2,3-dimethyl-3H,4H,5H,6H,7H-imidazo[4,5-c]pyridine | 4,4'-Bis(4,6-diphenyl-1,3,5-triazin-2-yl)biphenyl | Cyclosporin A (NSC 290193) | Fluorescein PEG NHS, FITC-PEG-NHS |
| Catalog Number | M612021 | D178285 | B152868 | C407869 | F163697 |
| Price | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |
| Description | Inquire | Inquire | Inquire | InformationCyclosporin A (NSC 290193) Cyclosporin A (Cyclosporine A, Cyclosporine, Ciclosporin, CsA) is an immunosuppressive agent, binds to the cyclophilin and then inhibits calcineurin with IC50 of 7 nM in a cell-free assay, widely used in organ transplantationIn vitroCyclosporin A binds to the InformationCyclosporin A (NSC 290193) Cyclosporin A (Cyclosporine A, Cyclosporine, Ciclosporin, CsA) is an immunosuppressive agent, binds to the cyclophilin and then inhibits calcineurin with IC50 of 7 nM in a cell-free assay, widely used in organ transplantationIn vitroCyclosporin A binds to the cyclophilin (immunophilin) in T cells, forms a Cyclophilin-Cyclosporin A complex which the binds to and inhibits calcineurin. Cyclosporin A inhibits calcineurin with IC50 of 7 nM, then blocks the nuclear translocation of NF-AT. Cyclosporin A also affects mitochondria by preventing the MTP (mitochondrial permeability transition pore) from opening with an IC50 of 39 nM.In vivoCyclosporin A is an immunosuppressive agent that is effective following either parenteral or oral administration in mice, rat and guinea pigs., is clinically used in organ transplantation to prevent rejection.Cell Datacell lines：Concentrations：~100 nMIncubation Time：1 hrPowder Purity:≥99%... Read More | Fluorescein labeled polyethylene glycol is a fluorescent PEG derivative which has a maximum absorption at 495 nm and emission around 515~520 nm. FITC group can be easily traced from its yellow color and green fluorescence. Additional functionality allows these fluorescent PEG derivatives to be Fluorescein labeled polyethylene glycol is a fluorescent PEG derivative which has a maximum absorption at 495 nm and emission around 515~520 nm. FITC group can be easily traced from its yellow color and green fluorescence. Additional functionality allows these fluorescent PEG derivatives to be easily conjugated to other molecule or material surfaces... Read More |
| Quantity | 5mg, 25mg | 250mg | 50mg, 200mg, 1g | 1ml | 250mg, 50mg |
| Type | Chelating Agents & Ligands | Chemical | Metals & Materials | Chelating Agents & Ligands | Chelating Agents & Ligands |
| Purity / Grade | Moligand™ | ≥97% | ≥95% | Moligand™, 10mM in DMSO | MW 3400 Da |
| SMILES | Inquire | CC1=NC2=C(N1C)CNCC2 | C1=CC=C(C=C1)C2=NC(=NC(=N2)C3=CC=C(C=C3)C4=CC=C(C=C4)C5=NC(=NC(=N5)C6=CC=CC=C6)C7=CC=CC=C7)C8=CC=CC=C8 | Inquire | Inquire |
| Molecular Formula | Inquire | C8H13N3 | C42H28N6 | C62H111N11O12 | Inquire |
| Applications | Inquire | Inquire | Inquire | Inquire | Inquire |
| Get Quote | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |