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| Company | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation |
| Item | Guanidine Sulfamate | 1-(Chloromethyl)-4-phenoxybenzene | Auranofin | Ethyl 5-methylindole-2-carboxylate | Tazobactam acid |
| Catalog Number | G156847 | C589025 | A423478 | E132164 | T195683 |
| Price | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |
| Description | Inquire | Inquire | Auranofin (Ridaura, SKF-39162) is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 µM. Auranofin is an FDA-approved gold-containing compound used Auranofin (Ridaura, SKF-39162) is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 µM. Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis.Auranofin inhibits both leukocyte activation pathways at multiple sites and the release of inflammatory mediators from human macrophages, basophils, and pulmonary mast cells. Auranofin also inhibits 5-lipoxygenase in human neutrophils, IKB kinase (IKK) by modifying Cys-179 of the IKKβ subunit 5 and selenoenzyme thioredoxin reductase (TrxR) which is involved in the defense against oxidative stress. Auranofin is a disease-modifying antirheumatic drug (DMARD) and has been used to study the anti-proliferative effects against OVCAR-3 human ovarian carcinoma cells... Read More | It is an indole derivative. Indole ring system is an important building block or intermediate in the synthesis of many pharmaceutical agents. It is formed during the Fischer indolization of ethyl pyruvate 2-[2-(methanesulfonyloxy)-4-methyl]phenylhydrazine.A compound for the synthesis of biological It is an indole derivative. Indole ring system is an important building block or intermediate in the synthesis of many pharmaceutical agents. It is formed during the Fischer indolization of ethyl pyruvate 2-[2-(methanesulfonyloxy)-4-methyl]phenylhydrazine.A compound for the synthesis of biological active chemicals... Read More | Inquire |
| Quantity | 100g, 500g, 25g | 250mg, 100mg, 1g | 1ml | 100g, 5g, 25g, 1g | 100g, 250mg, 5g, 25g, 1g |
| Type | Organic Compound | Organic Compound | Chelating Agents & Ligands | Aromatic Compound | Reagent |
| Purity / Grade | ≥90%(T) | ≥95% | Moligand™, 10mM in DMSO | ≥99% | Moligand™, ≥97, %≥97, Moligand™, ≥97, %%≥97% |
| SMILES | C(=N)(N)N.NS(=O)(=O)O | C1=CC=C(C=C1)OC2=CC=C(C=C2)CCl | CCP(CC)CC.CC(=O)OCC1C(C(C(C(O1)[S-])OC(=O)C)OC(=O)C)OC(=O)C.[Au+] | CCOC(=O)C1=CC2=C(N1)C=CC(=C2)C | C[C@@]1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3 |
| Molecular Formula | CH5N3·H3NO3S | C13H11ClO | C20H34AuO9PS | C12H13NO2 | C10H12N4O5S |
| Applications | Inquire | Inquire | Inquire | Inquire | Inquire |
| Get Quote | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |