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| Company | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation |
| Item | Pyrazine | (1R,2R)-(+)-1,2-Diphenylethylenediamine | (2S,3S)-1,4-Dioxaspiro[4.5]decane-2,3-diylbis(diphenylmethanol) | Auranofin | Boc-3,4-dimethoxy-l-phenylalanine |
| Catalog Number | P109614 | R115655 | S281722 | A423478 | B180962 |
| Price | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |
| Description | Inquire | product manual(1R,2R)-(+)-1,2-Diphenylethylenediamine (DPEN) is one of the widely used chiral auxiliary and ligand in the synthesis of asymmetric catalysts such as BINAP/diamine-Ru complexes for the stereoselective hydrogenation of ketones.It can be used in the preparation of monosulfonyl DPEN-salt product manual(1R,2R)-(+)-1,2-Diphenylethylenediamine (DPEN) is one of the widely used chiral auxiliary and ligand in the synthesis of asymmetric catalysts such as BINAP/diamine-Ru complexes for the stereoselective hydrogenation of ketones.It can be used in the preparation of monosulfonyl DPEN-salt to catalyze Michael addition of various ketones to maleimides.DPEN-derived chiral triazolium salts can be used to catalyze enantioselective intramolecular Stetter reaction and oxodiene Diels-Alder reaction.Zinc acetate complexes of DPEDA-derived ligands can also be used to catalyze hydrosilylation of imines... Read More | Inquire | Auranofin (Ridaura, SKF-39162) is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 µM. Auranofin is an FDA-approved gold-containing compound used Auranofin (Ridaura, SKF-39162) is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 µM. Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis.Auranofin inhibits both leukocyte activation pathways at multiple sites and the release of inflammatory mediators from human macrophages, basophils, and pulmonary mast cells. Auranofin also inhibits 5-lipoxygenase in human neutrophils, IKB kinase (IKK) by modifying Cys-179 of the IKKβ subunit 5 and selenoenzyme thioredoxin reductase (TrxR) which is involved in the defense against oxidative stress. Auranofin is a disease-modifying antirheumatic drug (DMARD) and has been used to study the anti-proliferative effects against OVCAR-3 human ovarian carcinoma cells... Read More | Inquire |
| Quantity | 100g, 50g, 500g, 10g | 100g, 10g, 25g, 250mg, 1g, 5g | 2g, 500mg | 1ml | 5g, 1g |
| Type | Organic Compound | Organic Compound | Chelating Agents & Ligands | Chelating Agents & Ligands | Chemical |
| Purity / Grade | ≥98% | ≥99% | ≥98% | Moligand™, 10mM in DMSO | ≥95% |
| SMILES | C1=CN=CC=N1 | C1=CC=C(C=C1)[C@H]([C@@H](C2=CC=CC=C2)N)N | C1CCC2(CC1)OC(C(O2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)C(C5=CC=CC=C5)(C6=CC=CC=C6)O | CCP(CC)CC.CC(=O)OCC1C(C(C(C(O1)[S-])OC(=O)C)OC(=O)C)OC(=O)C.[Au+] | CC(C)(C)OC(=O)N[C@@H](CC1=CC(=C(C=C1)OC)OC)C(=O)O |
| Molecular Formula | C4H4N2 | C14H16N2 | C₃₄H₃₄O₄ | C20H34AuO9PS | C16H23NO6 |
| Applications | Inquire | Inquire | Inquire | Inquire | Inquire |
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