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| Company | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation |
| Item | β-NADH | (R)-Benzyl 2-amino-3-hydroxypropionate hydrochloride | 3-Bromophenylacetonitrile | 4-Ethyl-1,3-dimethyl-1H-pyrazol-5-amine sesquihydrate | Auranofin |
| Catalog Number | N425025 | H587368 | B122843 | E482989 | A423478 |
| Price | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |
| Description | β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations... Read More | Benzyl D-serinate hydrochloride is a serine derivative | 3-Bromophenylacetonitrile has been used in the synthesis of: a series of aminoethylbiphenyls, novel 5-HT7 receptor ligands 2-(1-cyano-1-(3-bromophenyl))methylidene-3-phenylthiazolidine-4,5-dione | Inquire | Auranofin (Ridaura, SKF-39162) is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 µM. Auranofin is an FDA-approved gold-containing compound used Auranofin (Ridaura, SKF-39162) is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 µM. Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis.Auranofin inhibits both leukocyte activation pathways at multiple sites and the release of inflammatory mediators from human macrophages, basophils, and pulmonary mast cells. Auranofin also inhibits 5-lipoxygenase in human neutrophils, IKB kinase (IKK) by modifying Cys-179 of the IKKβ subunit 5 and selenoenzyme thioredoxin reductase (TrxR) which is involved in the defense against oxidative stress. Auranofin is a disease-modifying antirheumatic drug (DMARD) and has been used to study the anti-proliferative effects against OVCAR-3 human ovarian carcinoma cells... Read More |
| Quantity | 1ml | 100g, 5g, 25g, 1g | 100g, 5g, 10g, 25g | 1g | 1ml |
| Type | Reagent | Organic Compound | Organic Compound | Aromatic Compound | Chelating Agents & Ligands |
| Purity / Grade | 10mM in DMSO | ≥97% | ≥98% | Reagent Grade | Moligand™, 10mM in DMSO |
| SMILES | C1C=CN(C=C1C(=O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)([O-])OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O.[Na+].[Na+] | C1=CC=C(C=C1)COC(=O)[C@@H](CO)N.Cl | C1=CC(=CC(=C1)Br)CC#N | Inquire | CCP(CC)CC.CC(=O)OCC1C(C(C(C(O1)[S-])OC(=O)C)OC(=O)C)OC(=O)C.[Au+] |
| Molecular Formula | C21H27N7Na2O14P2 | C10H14ClNO3 | C8H6BrN | Inquire | C20H34AuO9PS |
| Applications | Inquire | Inquire | Inquire | Inquire | Inquire |
| Get Quote | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |