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| Company | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation | Aladdin Scientific Corporation |
| Item | α1A-AR Degrader 9c | CL-387785 | DFMTI | Fenobucarb | Fmoc-D-3,4-difluorophenylalanine |
| Catalog Number | A1429899 | C337834 | D647716 | F647916 | F182509 |
| Price | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |
| Description | α1A-AR Degrader 9c (compound 9c) is a potent, selective and reversible α1A-AR ( Adrenergic receptor ) PROTAC degrader, with a DC 50 of 2.86 µM. α1A-AR Degrader 9c induces α1A-AR degradation can be attributed to proteasomal degradation. α1A-AR Degrader 9c inhibits the α1A-AR Degrader 9c (compound 9c) is a potent, selective and reversible α1A-AR ( Adrenergic receptor ) PROTAC degrader, with a DC 50 of 2.86 µM. α1A-AR Degrader 9c induces α1A-AR degradation can be attributed to proteasomal degradation. α1A-AR Degrader 9c inhibits the proliferation of PC-3 cells, with an IC 50 of 6.12 µM. α1A-AR Degrader 9c shows antitumor activity, and can be used for prostate cancer research... Read More | CL-387,785 irreversibly inhibits EGF-receptor (EGFR) kinase activity as well as EGF-stimulated autophosphorylation of tyrosine residues in the EGFR. CL-387,785 also blocks EGF-mediated growth in A431 cells. The compound inhibits proliferation of EGFR or c-ErbB2 expressing cells by covalently bindingCL-387,785 irreversibly inhibits EGF-receptor (EGFR) kinase activity as well as EGF-stimulated autophosphorylation of tyrosine residues in the EGFR. CL-387,785 also blocks EGF-mediated growth in A431 cells. The compound inhibits proliferation of EGFR or c-ErbB2 expressing cells by covalently binding to the EGFR... Read More | DFMTI can completely block the rmGlu1 L757V glutamate response.In vitro: DFMTI can completely block the rmGlu1 L757V glutamate response, although significantly higher concentrations were required to induce blockade.In vivo: DFMTI is efficacious in disrupting prepulse inhibition when dosed orally in DFMTI can completely block the rmGlu1 L757V glutamate response.In vitro: DFMTI can completely block the rmGlu1 L757V glutamate response, although significantly higher concentrations were required to induce blockade.In vivo: DFMTI is efficacious in disrupting prepulse inhibition when dosed orally in rats. DFMTI exhibits a moderate decrease in human potency of approximately 3-fold when compared to rat, exemplified by DFMTI.Form:SolidIC50& Target:mGluR1... Read More | Fenobucarb is a carbamate insecticide. Fenobucarb induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis. Fenobucarb is a possible risk factor to cardiovascular and cerebrovascular systems in animals.Form:Oil | Inquire |
| Quantity | 5mg | 100mg, 500mg | 100mg, 5mg, 50mg, 1mg, 10mg | 250mg | 1g |
| Type | Bioactive Small Molecules | Chelating Agents & Ligands | Chelating Agents & Ligands | Chelating Agents & Ligands | Chemical |
| Purity / Grade | ≥99% | ≥97% | ≥99% | ≥99% | ≥97% |
| SMILES | Inquire | CC#CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=CC=C3)Br | Inquire | CCC(C)C1=CC=CC=C1OC(=O)NC | C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@H](CC4=CC(=C(C=C4)F)F)C(=O)O |
| Molecular Formula | C38H43N11O11 | C18H13BrN4O | C20H18F2N4O | C12H17NO2 | C24H19F2NO4 |
| Applications | Inquire | Inquire | Inquire | Inquire | Inquire |
| Get Quote | Supplier Page | Supplier Page | Supplier Page | Supplier Page | Supplier Page |