Dynamic light scattering particle size analyzers are used to measure the size of very small particles (0.6 nm to 6 um) in solution. This class of particle size analyzer interprets particles’ sizes from the fluctuations in scattered laser light created by the particles’ Brownian motion. Dynamic light scattering analysis is used in medical, biological research and materials science applications, and is also known as photon correlation spectroscopy or quasi-electron light scattering.
Although requiring suspension in a solution, particle size analysis by dynamic light scattering offers the advantage of measuring particles across a wide range of densities, from parts-per-million up to 40% of solution. Other advantages include size analysis of particles in their native environment and micro-liter scale minimum sample sizes. In addition, dynamic light scattering particle size analyzers may also provide information on particle shape and require less user training. Analysis times typically vary from 30 seconds to 2 minutes per sample.
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| Company | Brookhaven Instruments Corporation | Brookhaven Instruments Corporation |
| Item | NanoBrook Omni | NanoBrook Omni |
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| Description | Inquire | Brookhaven's NanoBrook Omni instrument combines the best technology from our particle/protein sizer and zeta potential analyzer in to one powerful and accurate solution for sizing and zeta potential analysis. Measure samples in nearly every possible suspension environment from high salts such as PBSBrookhaven's NanoBrook Omni instrument combines the best technology from our particle/protein sizer and zeta potential analyzer in to one powerful and accurate solution for sizing and zeta potential analysis. Measure samples in nearly every possible suspension environment from high salts such as PBS and sea water to organic solvents and of course aqueous solutions. Particle and protein sizing, with the highest sensitivity, utilizing three measurement angles for truly unbiased measurement results. The NanoBrook Omni utilizes a backscattering angle as well as 90° and 15°.
Features:
- Rapid and accurate protein & nanoparticle size distributions
- Multimodal & unimodal size distribution software
- ISO 13321 and ISO 22412 compliant results
- Three measurement angles: 15°, 90°, and 173°
- Ideal for fast, routine sizing applications in research or quality control
- Zeta potential for the difficult cases...
- For proteins, peptides, mAb, RNA and other biological samples
- For zeta potential in organic solvents
- For oily or viscous media
- For high-salt suspensions
- For samples near the I.E.P.
- 1,000 times more sensitive than other techniques
- Disposable cuvettes, no contamination or alignment
- Built in automatic procedures and parameters (SOP)
- Easy to use
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| Type | Dynamic Light Scattering (DLS) | Dynamic Light Scattering (DLS), Electrophoretic Light Scattering (ELS), Phase Analysis Light Scattering (PALS) |
| Particle Size | 0.3 nm to 10 µm | <0.6 nm to 10 um (at 173 degrees); 1 nm to 6 um (at 90 degrees) |
| Detector(s) | Avalanche Photodiode (APD) | Avalanche Photodiode (APD) |
| Measuring Time | 1-2 minutes typical | 1-2 minutes typical |
| Light Source | 40 mW red diode laser, 640 nm | 40 mW red diode laser, nominal 640 nm wavelength |
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