| Description | Human astrocytes (HA) are derived from the human cerebral cortex. Astrocytes are the most abundant cells in the central nervous system, where they perform many functions, such as providing mechanical support and nutrition to neurons and removing waste from neurons. Provide signals to endothelial Human astrocytes (HA) are derived from the human cerebral cortex. Astrocytes are the most abundant cells in the central nervous system, where they perform many functions, such as providing mechanical support and nutrition to neurons and removing waste from neurons. Provide signals to endothelial cells; regulate neurogenesis and control synaptic function. With the increasing understanding of the importance of astrocytes in the nervous system, HA has become a useful in vitro model for exploring the functional diversity of astrocytes.... Read More | Anaerostipes is a Gram positive and anaerobic bacterial genus from the family of Lachnospiraceae. Anaerostipes occurs in the human gut. It may protect against colon cancer in humans by producing butyric acid. | Recombinant Ebola Virus-like Particles (EBOV VLPs) are produced in mammalian HEK293 human cells, assembled with Nucleoprotein, Glycoprotein and Matrix protein. VLP is mimicking the native 3D structure of viruses which can elicit strong immune responses. However, VLPs lack viral genomic material Recombinant Ebola Virus-like Particles (EBOV VLPs) are produced in mammalian HEK293 human cells, assembled with Nucleoprotein, Glycoprotein and Matrix protein. VLP is mimicking the native 3D structure of viruses which can elicit strong immune responses. However, VLPs lack viral genomic material which makes them non-infectious, unable to replicate and enhance the safety during manufacture and administration. EBOV VLPs can be used in the development of EBOV diagnostics and in vaccine development and R&D (including use as an immunogen).... Read More | Creative Biolabs Human iPSC-Sensory Neuron Progenitors are derived from integration-free iPSCs and have been differentiated to neurons using small molecules. We offer a fully optimized cell culture system including tailored Sensory Maintenance Medium and coating reagents to promote the viability andCreative Biolabs Human iPSC-Sensory Neuron Progenitors are derived from integration-free iPSCs and have been differentiated to neurons using small molecules. We offer a fully optimized cell culture system including tailored Sensory Maintenance Medium and coating reagents to promote the viability and maturation of sensory neurons for endpoint assays on glass or plastic.
Our iPSC-derived sensory neurons express several voltage-gated sodium ion channels and transient receptor potential (TRP) ion channels that play a key role in nociception. These include sodium ion channels Nav1.7 and the DRG-specific, TTX-resistant channels, Nav1.8 and Nav1.9 as well as the temperature-sensitive, TRPV1 and TRPM8, and TRPA1, a sensor of pungency, bitterness and cold.
Creative Biolabs iPSC-Derived Sensory Neuron Progenitors are available in large batch sizes for reliable and consistent results in high-throughput screening assays. The cells are also suitable for investigating disorders of the peripheral nervous system and chronic pain as well as drug targets for pain relief.... Read More | The product SIRGT00060WQ is a type of small interfering RNA (siRNA) that targets ADA gene and regulates the expression of gene. The siRNA interferes with the expression of ADA gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has potentialThe product SIRGT00060WQ is a type of small interfering RNA (siRNA) that targets ADA gene and regulates the expression of gene. The siRNA interferes with the expression of ADA gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More |