| Description | Creative Biolabs Human iPSC-Sensory Neuron Progenitors are derived from integration-free iPSCs and have been differentiated to neurons using small molecules. We offer a fully optimized cell culture system including tailored Sensory Maintenance Medium and coating reagents to promote the viability andCreative Biolabs Human iPSC-Sensory Neuron Progenitors are derived from integration-free iPSCs and have been differentiated to neurons using small molecules. We offer a fully optimized cell culture system including tailored Sensory Maintenance Medium and coating reagents to promote the viability and maturation of sensory neurons for endpoint assays on glass or plastic.
Our iPSC-derived sensory neurons express several voltage-gated sodium ion channels and transient receptor potential (TRP) ion channels that play a key role in nociception. These include sodium ion channels Nav1.7 and the DRG-specific, TTX-resistant channels, Nav1.8 and Nav1.9 as well as the temperature-sensitive, TRPV1 and TRPM8, and TRPA1, a sensor of pungency, bitterness and cold.
Creative Biolabs iPSC-Derived Sensory Neuron Progenitors are available in large batch sizes for reliable and consistent results in high-throughput screening assays. The cells are also suitable for investigating disorders of the peripheral nervous system and chronic pain as well as drug targets for pain relief.... Read More | Creative Biolabs' Alzheimer's Disease Brain Tissue Panel (TeHAD-Alz) is designed to rapidly screen brain tissue for Alzheimer's disease-specific genes or proteins. | Creative Biolabs' Neuropathy Frozen Tissue Panels are designed for the study of Alzheimer's disease, Parkinson's disease, dementia, multiple sclerosis, progressive supranuclear palsy (PSP) and depression. | This membrane protein is Human DNAM-1 / CD226 (19-247). It has been tested in SDS-PAGE, ELISA, BLI, FACS. We provide this protein to facilitate your membrane protein antibody discovery and development. | The product SIRGT41440WQ-2OMe is a type of small interfering RNA (siRNA) that targets HRASLS2 gene and regulates the expression of gene. The siRNA interferes with the expression of HRASLS2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. TheThe product SIRGT41440WQ-2OMe is a type of small interfering RNA (siRNA) that targets HRASLS2 gene and regulates the expression of gene. The siRNA interferes with the expression of HRASLS2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2_-O-methyl (2'-OMe) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More |