| Description | Baboon are large, robust, and primarily terrrestrial monkeys with orthographic processing abilities. This product is isolated from Baboons Dermis Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and assays such as PCR, Western Baboon are large, robust, and primarily terrrestrial monkeys with orthographic processing abilities. This product is isolated from Baboons Dermis Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and assays such as PCR, Western blot, immunoprecipitation, immunofluorescent flow cytometry.... Read More | Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from Cynomolgus monkeys Stomach Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from Cynomolgus monkeys Stomach Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and assays such as PCR, Western blot, immunoprecipitation, immunofluorescent flow cytometry.... Read More | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the P301L mutation (CCG>CTG) into the MAPT gene. This line is homozygous for the P301L mutation so both alleles contain the mutation. Click on the product images to see the data and Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the P301L mutation (CCG>CTG) into the MAPT gene. This line is homozygous for the P301L mutation so both alleles contain the mutation. Click on the product images to see the data and further details.
The P301L mutation MAPT has been implicated in frontotemporal dementia and parkinsonism (Dumanchin et al., 1998). The mutation affects only the 4R isoforms of MAPT since the exon containing the mutation is spliced out of 3R isoforms (Hutton et al., 1998). Aggregated MAPT/tau protein in affected patients consisted mainly of the 4R isoform (Hutton et al., 1998). The P301L mutation promotes aggregation of MAPT/tau protein into ordered paired helical filaments and beta sheet formation in vitro (von Bergen et al., 2001).... Read More | This product GTTS-WK5890MR is a type of mRNA having 30 nt poly(A) tail and modified with Cap 1 & N1-Methylpseudo-UTP. It ecodes the IL-4 protein. This product can be used in -related researches. | The product SIRGT95067WQ is a type of small interfering RNA (siRNA) that targets Coq4 gene and regulates the expression of gene. The siRNA interferes with the expression of Coq4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has The product SIRGT95067WQ is a type of small interfering RNA (siRNA) that targets Coq4 gene and regulates the expression of gene. The siRNA interferes with the expression of Coq4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More |