| Description | Squirrel monkeys are New World monkeys that habitat in the tropical forests of America, and can be used for pet trade and medical research. This product is collected from Squirrel monkeys Veins or arteries tissue. The sample is negative for Herpes B Virus, retroviruses, SIV, SRV, & STLV. It can be Squirrel monkeys are New World monkeys that habitat in the tropical forests of America, and can be used for pet trade and medical research. This product is collected from Squirrel monkeys Veins or arteries tissue. The sample is negative for Herpes B Virus, retroviruses, SIV, SRV, & STLV. It can be applied for life science laboratory or biochemical experiment such as PCR, Western blot, immunoprecipitation, immunofluorescent flow cytometry and Biomarker Discovery.... Read More | The Eggerthellaceae are a family of Gram-positive, rod- or coccus-shaped Actinobacteria. It is the sole family within the order Eggerthellales. Members of this family are mostly anaerobic, non-motile, asaccharolytic and do not form spores. Eggerthellaceae species are commonly isolated from human andThe Eggerthellaceae are a family of Gram-positive, rod- or coccus-shaped Actinobacteria. It is the sole family within the order Eggerthellales. Members of this family are mostly anaerobic, non-motile, asaccharolytic and do not form spores. Eggerthellaceae species are commonly isolated from human and animal faeces and other human sources such as the colon, vagina, oral cavity and blood.... Read More | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the P301L mutation (CCG>CTG) into the MAPT gene. This line is homozygous for the P301L mutation so both alleles contain the mutation. Click on the product images to see the data and Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the P301L mutation (CCG>CTG) into the MAPT gene. This line is homozygous for the P301L mutation so both alleles contain the mutation. Click on the product images to see the data and further details.
The P301L mutation MAPT has been implicated in frontotemporal dementia and parkinsonism (Dumanchin et al., 1998). The mutation affects only the 4R isoforms of MAPT since the exon containing the mutation is spliced out of 3R isoforms (Hutton et al., 1998). Aggregated MAPT/tau protein in affected patients consisted mainly of the 4R isoform (Hutton et al., 1998). The P301L mutation promotes aggregation of MAPT/tau protein into ordered paired helical filaments and beta sheet formation in vitro (von Bergen et al., 2001).... Read More | Creative Biolabs offers the overexpression cell line which expressing the co-inhibitory and co-stimulatory immune checkpoints of human, mouse and cynomolgus monkey origin to accelerate immunotherapy discovery and development. | The product SIRGT63524WQ-2MOE is a type of small interfering RNA (siRNA) that targets PIKFYVE gene and regulates the expression of gene. The siRNA interferes with the expression of PIKFYVE gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. TheThe product SIRGT63524WQ-2MOE is a type of small interfering RNA (siRNA) that targets PIKFYVE gene and regulates the expression of gene. The siRNA interferes with the expression of PIKFYVE gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More |