| Description | Squirrel monkeys are New World monkeys that habitat in the tropical forests of America, and can be used for pet trade and medical research. This product is isolated from Squirrel monkey fresh whole blood tissue. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a varietySquirrel monkeys are New World monkeys that habitat in the tropical forests of America, and can be used for pet trade and medical research. This product is isolated from Squirrel monkey fresh whole blood tissue. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays such as cell-cell interaction, adhesion, migration, PCR, Western blot, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry, or generating cell derivatives for desired research applications.... Read More | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in autosomal-dominant familial Parkinson's disease with late onset (Fonzo et al., 2006, Thaler et al., 2009). The G2019S mutation increases the kinase activity of LRRK2 causing increased autophosphorylation and substrate phosphorylation that may affect neuronal cell health in Parkinson's disease patients (West et al., 2005).... Read More | This product GTTS-WK5849MR is a type of mRNA having 30 nt poly(A) tail and modified with Cap 1 & N1-Methylpseudo-UTP. It ecodes the IL7R protein. This product can be used in -related researches. | Rabbit corneal epithelial cells (RbCEpC) are isolated from rabbit corneal epithelial tissue, which covers and protects the cornea from bacteria and other harmful organisms and substances. RbCEpC is cryopreserved in the X generation, and is cultivated and propagated at least when the X population hasRabbit corneal epithelial cells (RbCEpC) are isolated from rabbit corneal epithelial tissue, which covers and protects the cornea from bacteria and other harmful organisms and substances. RbCEpC is cryopreserved in the X generation, and is cultivated and propagated at least when the X population has doubled.... Read More | The product SIRGT83828WQ-2MOE is a type of small interfering RNA (siRNA) that targets Rfc4 gene and regulates the expression of gene. The siRNA interferes with the expression of Rfc4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNAThe product SIRGT83828WQ-2MOE is a type of small interfering RNA (siRNA) that targets Rfc4 gene and regulates the expression of gene. The siRNA interferes with the expression of Rfc4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2'-O-methoxyethyl (2'-MOE) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More |