| Description | Human trabecular meshwork cells (HTMC) are endothelial-like cells in the spongy connective tissue located in the front of the eye.htmC forms a layer of light beam, which is part of the fibrous basement membrane that contains the extracellular matrix and cells. In areas of high resistance to outflow.Human trabecular meshwork cells (HTMC) are endothelial-like cells in the spongy connective tissue located in the front of the eye.htmC forms a layer of light beam, which is part of the fibrous basement membrane that contains the extracellular matrix and cells. In areas of high resistance to outflow.htmC regulates intraocular pressure by controlling the drainage of fluid into the tube that flows into the blood. Changes i.htmC contractility and tension mediate outflow. Due to its phagocytosis.htmC can also be used as a self-cleaning filter. Live cell imaging of the cytoskeleton provides valuable information for actin dynamics i.htmC. Other research aims to identify treatments that rela.htmC contractions to increase fluid outflow and reduce intraocular pressure. The specific targeting effect o.htmC can also play a clinical role by increasing the therapeutic efficacy of nanoparticles for gene delivery.... Read More | Alistipes is a relatively new genus of bacteria isolated primarily from medical clinical samples, although at a low rate compared to other genus members of the Bacteroidetes phylum, which are highly relevant in dysbiosis and disease. | Bacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. BacteroidesBacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. Bacteroides; order is the most abundant group of Gram-negative bacteria which flourish in the human intestine at high densities of 109-1011 CFU per gram of feces, and constitutes over 30 species which are more closely related than members in other bacteria orders. And, Bacteroides is considered as one of the major genera of the core microbiota module, of which species with relative abundance of over 1% refers to B. uniformis, B. vulgatus, B. caccae, and B. thetaiotaomicron. In addition to the unique physiological characteristics and the special ecological dynamics, Bacteroides species are under investigations for their underlying beneficial dialogues with the host. Bacteroides species to be considered as next-generation probiotics, and the application of which in prevention or intervention in dysbiosis of gut microbiota and the associated disorders requires further investigations in the modulatory mechanisms and safety evaluation. Bacteroides is one of the dominant contributors of SCFA among the intestinal commensals, mostly in the form of acetate and propionate. Accumulated acetate blocks the transportation of toxins between gut lumen and blood, while propionate is capable of inducing the apoptosis of human colon carcinoma cells, and thus avoids the formation of tumors. Moreover, Vitamin K, which is mainly synthesized by gut microbiota candidates such as Bacteroides, can help prevent or treat osteoporosis by increasing bone mineral density.... Read More | This product is a 64.0kDa Human DSG3 membrane protein expressed in E.coli. The protein is for research use only and is not approved for use in humans or in clinical diagnosis. | The product SIRGT47166WQ-2F is a type of small interfering RNA (siRNA) that targets LIN28A gene and regulates the expression of gene. The siRNA interferes with the expression of LIN28A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The The product SIRGT47166WQ-2F is a type of small interfering RNA (siRNA) that targets LIN28A gene and regulates the expression of gene. The siRNA interferes with the expression of LIN28A gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2_-deoxy-2_-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More |