| Description | The product SIRGT15930WQ is a type of small interfering RNA (siRNA) that targets ROBO2 gene and regulates the expression of gene. The siRNA interferes with the expression of ROBO2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has The product SIRGT15930WQ is a type of small interfering RNA (siRNA) that targets ROBO2 gene and regulates the expression of gene. The siRNA interferes with the expression of ROBO2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More | Creative Biolabs' frozen tissue slides are ideal for rapid identification of the cellular localization of RNA or proteins. Additional organs are available upon request. | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in autosomal-dominant familial Parkinson's disease with late onset (Fonzo et al., 2006, Thaler et al., 2009). The G2019S mutation increases the kinase activity of LRRK2 causing increased autophosphorylation and substrate phosphorylation that may affect neuronal cell health in Parkinson's disease patients (West et al., 2005).... Read More | This membrane protein is Human DNAM-1 / CD226 (19-247). It has been tested in SDS-PAGE, ELISA, BLI, FACS. We provide this protein to facilitate your membrane protein antibody discovery and development. | Marmoset monkeys are tree-dwelling small monkeys that habitat South American. This product is isolated from Marmosets Fallopian Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and assays such as PCR, Western blot, Marmoset monkeys are tree-dwelling small monkeys that habitat South American. This product is isolated from Marmosets Fallopian Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and assays such as PCR, Western blot, immunoprecipitation, immunofluorescent flow cytometry.... Read More |