| Description | The human striatum receives dopaminergic and glutamatergic inputs from different parts of the central nervous system, and is the primary input nucleus of the basal ganglia. The striatum plays key roles in coordinating various brain functions, including motivation and motor planning.
The vast The human striatum receives dopaminergic and glutamatergic inputs from different parts of the central nervous system, and is the primary input nucleus of the basal ganglia. The striatum plays key roles in coordinating various brain functions, including motivation and motor planning.
The vast majority of human striatal neurons are _-amino butyric acid (GABAergic) projection medium spiny neurons (MSNs). These cells typically express dopamine- and cAMP-regulated phosphoprotein - DARPP32. It is these cells that specifically degenerate in the early phase of Huntington's disease (HD) causing progressive loss of the patients' motor and cognitive functions.
Creative Biolabs has developed a medium formulation that can efficiently drive the differentiation of iPSC-derived neural stem cells to striatal neuronal lineage. The neurons derived using the medium kit are functionally active and express key markers of human MSNs, such as DARPP32, CTIP2, CALBINDIN and GABA.... Read More | Creative Biolabs' Neuropathy Frozen Tissue Panels are designed for the study of Alzheimer's disease, Parkinson's disease, dementia, multiple sclerosis, progressive supranuclear palsy (PSP) and depression. | Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from Cynomolgus Cynomolgus monkey spleen tissue. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from Cynomolgus Cynomolgus monkey spleen tissue. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays such as cell-cell interaction, adhesion, migration, PCR, Western blot, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry, or generating cell derivatives for desired research applications.... Read More | Creative Biolabs offers a range of recombinant cell lines for Immunotherapy discovery and development. | This product GTVCR-WQ1499MR is an effective transcription system suitable for a variety of research, including the in vitro translation, self-amplifying mRNA studies and protein expression. The system was driven by the T7 promoter to efficiently generate mRNA with 30 nt poly(A) tail ecoding antibodyThis product GTVCR-WQ1499MR is an effective transcription system suitable for a variety of research, including the in vitro translation, self-amplifying mRNA studies and protein expression. The system was driven by the T7 promoter to efficiently generate mRNA with 30 nt poly(A) tail ecoding antibody which targeting IL1RL2. The vector contains the self-replicating Venezuelan equine encephalitis (VEE) virus RNA replicon, which resulting the mRNA expression at a high level.... Read More |