| Description | Ruminococcus is a genus of bacteria in the class Clostridia. They are anaerobic, Gram-positive gut microbes. One or more species in this genus are found in significant numbers in the human gut microbiota. | Clostridium is a genus of rod-shaped, usually Gram-positive bacteria, members of which are found in soil, water, and the intestinal tracts of humans and other animals. The majority of species are obligate anaerobes. As the predominant bacteria in gut, Clostridium species exert lots of benefits to Clostridium is a genus of rod-shaped, usually Gram-positive bacteria, members of which are found in soil, water, and the intestinal tracts of humans and other animals. The majority of species are obligate anaerobes. As the predominant bacteria in gut, Clostridium species exert lots of benefits to body health via interacting with intestine directly or indirectly. Clostridium species are potent candidates to alleviate dysfunctions and disorders in intestine, they have been reported to attenuate inflammation and allergic diseases effectively owing to their distinctive biological activities. Their cellular components and metabolites, like butyrate, secondary bile acids and indolepropionic acid, play a probiotic role primarily through energizing intestinal epithelial cells, strengthening intestinal barrier and interacting with immune system. In view of their salutary performances, Clostridium species have a huge potential as probiotics.... Read More | Creative Biolabs offers the overexpression Raji cells that stably express immune checkpoints. | Parabacteroides is a Gram-negative, anaerobic, non-spore-forming genus from the family Tannerellaceae. Currently, the genus Parabacteroides includes eight valid species with standing in nomenclature. The species Parabacteroides faecis and Parabacteroides johnsonii; faeces and Parabacteroides Parabacteroides is a Gram-negative, anaerobic, non-spore-forming genus from the family Tannerellaceae. Currently, the genus Parabacteroides includes eight valid species with standing in nomenclature. The species Parabacteroides faecis and Parabacteroides johnsonii; faeces and Parabacteroides gordonii; blood were all isolated for the first time in humans. Of all the species, Parabacteroides distasonis is the reference type strain for the genus Parabacteroides. To date, Parabacteroides distasonis has been shown to have beneficial effects on colorectal cancer. Multiple researchers have identified that levels of Parabacteroides distasonis in stool are inversely correlated to the presence of intestinal tumors. The evidence for the potential anti-inflammatory effects of Parabacteroides distasonis in colorectal cancer is further supported by the inverse correlation between Parabacteroides distasonis levels and IL-1β production in the gut, suggesting that Parabacteroides distasonis has anti-tumorigenic and anti-inflammatory potential in colorectal cancer patients. Further potential benefits of Parabacteroides distasonis have been identified, particularly in relation to obesity. In addition, several studies have suggested that Parabacteroides distasonis may play a role in various forms of autoimmunity.... Read More | The product SIRGT83828WQ-2MOE is a type of small interfering RNA (siRNA) that targets Rfc4 gene and regulates the expression of gene. The siRNA interferes with the expression of Rfc4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNAThe product SIRGT83828WQ-2MOE is a type of small interfering RNA (siRNA) that targets Rfc4 gene and regulates the expression of gene. The siRNA interferes with the expression of Rfc4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2'-O-methoxyethyl (2'-MOE) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More |