| Description | This product is a 410 kDa native human C1q protein isolated from normal human serum. It is availible for ELISA, Functional Assays. | Chimpanzees are social animals most closely related to the human, they could be used in biomedical research repeatedly over decades. This product is isolated from Chimpanzees Epidermis Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of Chimpanzees are social animals most closely related to the human, they could be used in biomedical research repeatedly over decades. This product is isolated from Chimpanzees Epidermis Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and assays such as PCR, Western blot, immunoprecipitation, immunofluorescent flow cytometry.... Read More | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in autosomal-dominant familial Parkinson's disease with late onset (Fonzo et al., 2006, Thaler et al., 2009). The G2019S mutation increases the kinase activity of LRRK2 causing increased autophosphorylation and substrate phosphorylation that may affect neuronal cell health in Parkinson's disease patients (West et al., 2005).... Read More | Creative Biolabs offers a range of recombinant cell lines for Immunotherapy discovery and development. | This product is a 21.4kDa recombinant mouse Ficolin 2 protein with a N-terminal His Tag tag expressed in the E.coli. It is availible for Positive Control, Immunogen, WB. |