| Description | Researchers at the Creative Biolabs have developed BALB/c Mouse CD3 Pan T Cells, purified that allows for study in numerous research areas, such as immunology, oncology. The cells can be used for a wide variety of safety assessment and functional assays. | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the P301L mutation (CCG>CTG) into the MAPT gene. This line is homozygous for the P301L mutation so both alleles contain the mutation. Click on the product images to see the data and Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the P301L mutation (CCG>CTG) into the MAPT gene. This line is homozygous for the P301L mutation so both alleles contain the mutation. Click on the product images to see the data and further details.
The P301L mutation MAPT has been implicated in frontotemporal dementia and parkinsonism (Dumanchin et al., 1998). The mutation affects only the 4R isoforms of MAPT since the exon containing the mutation is spliced out of 3R isoforms (Hutton et al., 1998). Aggregated MAPT/tau protein in affected patients consisted mainly of the 4R isoform (Hutton et al., 1998). The P301L mutation promotes aggregation of MAPT/tau protein into ordered paired helical filaments and beta sheet formation in vitro (von Bergen et al., 2001).... Read More | This product is a Human LAMP5 membrane protein expressed in HEK293. | Marmoset monkeys are tree-dwelling small monkeys that habitat South American. This product is isolated from Marmosets Bladder Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and assays such as PCR, Western blot, Marmoset monkeys are tree-dwelling small monkeys that habitat South American. This product is isolated from Marmosets Bladder Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and assays such as PCR, Western blot, immunoprecipitation, immunofluorescent flow cytometry.... Read More | This product is a recombinant mouse C3aR protein with a rho-1D4 tag tag expressed in the Insect Cells. It is availible for Crys, ELISA, WB. |