| Description | Human adipocytes (HPAd) provide an ideal cell model and facilitate life science research and drug discovery for obesity, diabetes and cardiovascular diseases. We extract HPAd from human subcutaneous and cardiac adipose tissue, and cryopreserve these fibroblast-like precursor cells at the end of the Human adipocytes (HPAd) provide an ideal cell model and facilitate life science research and drug discovery for obesity, diabetes and cardiovascular diseases. We extract HPAd from human subcutaneous and cardiac adipose tissue, and cryopreserve these fibroblast-like precursor cells at the end of the primary culture. They can be transmitted for two passages before differentiating into human adipocytes (HAd). Complete differentiation can be easily achieved by using pre-adipocyte differentiation medium. It is expected that mature HAd should remain healthy 10 days after differentiation induction and should respond within at least 2 weeks after full differentiation. The fat mass can be controlled by inhibiting the differentiation of HPAd and increasing the lipolysis effect. HPAd can also be pre-screened to express adipocyte markers.... Read More | Bifidobacterium are Gram-positive, heterofermentative, anaerobic bacteria with a distinctive bifid; i.e. Y shape after which they are named. They wre originally isolated from the faeces of breast-fed infants, members of the genus Bifidobacterium are commonly found in the GI tract of mammals. In Bifidobacterium are Gram-positive, heterofermentative, anaerobic bacteria with a distinctive bifid; i.e. Y shape after which they are named. They wre originally isolated from the faeces of breast-fed infants, members of the genus Bifidobacterium are commonly found in the GI tract of mammals. In humans, Bifidobacterium resides within the GI tract, from birth to old age. Disturbances in the microbiota are linked to an ever-growing number of immune-linked disease states including IBD, atopic allergy, arthritis, and obesity. Therefore, there is a significant interest in treating these diseases through microbial or "probiotic" supplementation of patients, including Bifidobacterium. Data from mouse models and clinical trials indicate that Bifidobacterium may have beneficial effects for treating and preventing immune-linked diseases, including gut-associated and systemic conditions. Bifidobacterium have been commercially exploited as probiotic agents due to their associated health benefits and GRAS.... Read More | Creative Biolabs offers the overexpression cell line which expressing the co-inhibitory and co-stimulatory immune checkpoints of human, mouse and cynomolgus monkey origin to accelerate immunotherapy discovery and development. | Creative Biolabs offers the overexpression cell line which expressing the co-inhibitory and co-stimulatory immune checkpoints of human, mouse and cynomolgus monkey origin to accelerate immunotherapy discovery and development. | This product is a made-to-order Human PAQR4 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis. |