| Description | The product SIRGT17403WQ-2F is a type of small interfering RNA (siRNA) that targets PKP2 gene and regulates the expression of gene. The siRNA interferes with the expression of PKP2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA The product SIRGT17403WQ-2F is a type of small interfering RNA (siRNA) that targets PKP2 gene and regulates the expression of gene. The siRNA interferes with the expression of PKP2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is designed with 2_-deoxy-2_-fluoro (2'-F) modification to provide increased stability, increased specificity and reduced immunogenicity. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More | Bifidobacterium are Gram-positive, heterofermentative, anaerobic bacteria with a distinctive bifid; i.e. Y shape after which they are named. They wre originally isolated from the faeces of breast-fed infants, members of the genus Bifidobacterium are commonly found in the GI tract of mammals. In Bifidobacterium are Gram-positive, heterofermentative, anaerobic bacteria with a distinctive bifid; i.e. Y shape after which they are named. They wre originally isolated from the faeces of breast-fed infants, members of the genus Bifidobacterium are commonly found in the GI tract of mammals. In humans, Bifidobacterium resides within the GI tract, from birth to old age. Disturbances in the microbiota are linked to an ever-growing number of immune-linked disease states including IBD, atopic allergy, arthritis, and obesity. Therefore, there is a significant interest in treating these diseases through microbial or "probiotic" supplementation of patients, including Bifidobacterium. Data from mouse models and clinical trials indicate that Bifidobacterium may have beneficial effects for treating and preventing immune-linked diseases, including gut-associated and systemic conditions. Bifidobacterium have been commercially exploited as probiotic agents due to their associated health benefits and GRAS; Generally Recognised As Safe status.... Read More | iNeuO2™ is a fluorescent biosensor that has been integrated into iNeuRapid™, iNeu's proprietary immortalized human neuroepithelial cell line. Biosensor assays provide fast kinetics (resolution: several seconds to several hours) when measuring real-time cell metabolism and cytotoxicity. iNeuO2™ is a fluorescent biosensor that has been integrated into iNeuRapid™, iNeu's proprietary immortalized human neuroepithelial cell line. Biosensor assays provide fast kinetics (resolution: several seconds to several hours) when measuring real-time cell metabolism and cytotoxicity. The analysis of cell respiration directly reflects the health and function of mitochondria.
iNeuO2™-Rapid cells can be used as a control for all products containing iNeuO2™ biosensor. In order to customize iNeuRapid™ cells according to the experimental needs of scientists, these cells can be easily transfected with the target gene. For other human cell lines and human cell types, please contact us.... Read More | Creative Biolabs offers a range of recombinant cell lines for Immunotherapy discovery and development. | This product GTTS-WQ2724MR is a type of mRNA having 120 nt poly(A) tail and modified with Cap 1 & 5-Methyl-CTP & Pseudo-UTP. It ecodes the monoclonal antibody that targets IL23A gene. The antibody can be applied in Crohn's disease (CD) research. |