| Description | This product is a 64.46 kDa Human CXCR4 membrane protein expressed in in vitro wheat germ expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis. | African Green Monkey has long been one of the most important non-human primate models for biomedical research which is close to Rhesus monkey. This product is isolated from African Green Monkeys Endocrine Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be usedAfrican Green Monkey has long been one of the most important non-human primate models for biomedical research which is close to Rhesus monkey. This product is isolated from African Green Monkeys Endocrine Tissue. The sample is negative for Herpes-B Virus, as well as SRV, SIV, STLV-1, and can be used for a variety of tests and assays such as PCR, Western blot, immunoprecipitation, immunofluorescent flow cytometry.... Read More | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the P301L mutation (CCG>CTG) into the MAPT gene. This line is homozygous for the P301L mutation so both alleles contain the mutation. Click on the product images to see the data and Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the P301L mutation (CCG>CTG) into the MAPT gene. This line is homozygous for the P301L mutation so both alleles contain the mutation. Click on the product images to see the data and further details.
The P301L mutation MAPT has been implicated in frontotemporal dementia and parkinsonism (Dumanchin et al., 1998). The mutation affects only the 4R isoforms of MAPT since the exon containing the mutation is spliced out of 3R isoforms (Hutton et al., 1998). Aggregated MAPT/tau protein in affected patients consisted mainly of the 4R isoform (Hutton et al., 1998). The P301L mutation promotes aggregation of MAPT/tau protein into ordered paired helical filaments and beta sheet formation in vitro (von Bergen et al., 2001).... Read More | Recombinant Norovirus GII.4 Virus-like Particles (NoV GII.4 VLPs) are produced in Insect cell expression system, assembled with VP1 structure protein. VLP is mimicking the native 3D structure of viruses which can elicit strong immune responses. However, VLPs lack viral genomic material which makes Recombinant Norovirus GII.4 Virus-like Particles (NoV GII.4 VLPs) are produced in Insect cell expression system, assembled with VP1 structure protein. VLP is mimicking the native 3D structure of viruses which can elicit strong immune responses. However, VLPs lack viral genomic material which makes them non-infectious, unable to replicate and enhance the safety during manufacture and administration. NoV GII.4 VLPs can be used in the development of NoV GII.4 diagnostics and in vaccine development and R&D (including use as an immunogen).... Read More | Rhesus Monkey is widely used in medical and biological research on human and animal related diseases even space travel due to its closeness to humans anatomically and physiologically. This product is isolated from Rhesus Monkey fresh peripheral blood mononuclear cell under sterile conditions. Cells Rhesus Monkey is widely used in medical and biological research on human and animal related diseases even space travel due to its closeness to humans anatomically and physiologically. This product is isolated from Rhesus Monkey fresh peripheral blood mononuclear cell under sterile conditions. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of studies in immunology, infectious diseases, cancer therapy, etc.... Read More |