| Description | Alistipes is a relatively new genus of bacteria isolated primarily from medical clinical samples, although at a low rate compared to other genus members of the Bacteroidetes phylum, which are highly relevant in dysbiosis and disease. | Bacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. BacteroidesBacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. Bacteroides; order is the most abundant group of Gram-negative bacteria which flourish in the human intestine at high densities of 109-1011 CFU per gram of feces, and constitutes over 30 species which are more closely related than members in other bacteria orders. And, Bacteroides is considered as one of the major genera of the core microbiota module, of which species with relative abundance of over 1% refers to B. uniformis, B. vulgatus, B. caccae, and B. thetaiotaomicron. In addition to the unique physiological characteristics and the special ecological dynamics, Bacteroides species are under investigations for their underlying beneficial dialogues with the host. Bacteroides species to be considered as next-generation probiotics, and the application of which in prevention or intervention in dysbiosis of gut microbiota and the associated disorders requires further investigations in the modulatory mechanisms and safety evaluation. Bacteroides is one of the dominant contributors of SCFA among the intestinal commensals, mostly in the form of acetate and propionate. Accumulated acetate blocks the transportation of toxins between gut lumen and blood, while propionate is capable of inducing the apoptosis of human colon carcinoma cells, and thus avoids the formation of tumors. Moreover, Vitamin K, which is mainly synthesized by gut microbiota candidates such as Bacteroides, can help prevent or treat osteoporosis by increasing bone mineral density.... Read More | Researchers at the Creative Biolabs have developed BALB/c Mouse PBMCs that allows for study in numerous research areas, such as immunology, oncology. The cells can be used for a wide variety of safety assessment and functional assays. | Recombinant Ebola Virus-like Particles (EBOV VLPs) are produced in mammalian HEK293 human cells, assembled with Nucleoprotein, Glycoprotein and Matrix protein. VLP is mimicking the native 3D structure of viruses which can elicit strong immune responses. However, VLPs lack viral genomic material Recombinant Ebola Virus-like Particles (EBOV VLPs) are produced in mammalian HEK293 human cells, assembled with Nucleoprotein, Glycoprotein and Matrix protein. VLP is mimicking the native 3D structure of viruses which can elicit strong immune responses. However, VLPs lack viral genomic material which makes them non-infectious, unable to replicate and enhance the safety during manufacture and administration. EBOV VLPs can be used in the development of EBOV diagnostics and in vaccine development and R&D (including use as an immunogen).... Read More | The product SIRGT90970WQ is a type of small interfering RNA (siRNA) that targets Plcl2 gene and regulates the expression of gene. The siRNA interferes with the expression of Plcl2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has The product SIRGT90970WQ is a type of small interfering RNA (siRNA) that targets Plcl2 gene and regulates the expression of gene. The siRNA interferes with the expression of Plcl2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More |