| Description | HPAd are prescreened for Adipogenesis Signaling: Primary cultures of adipocytes are prepared by inducing differentiation of human primary preadipocytes and are prescreened for the expression of the following major adipocyte markers:
PPAR_ (Peroxisome proliferator-activated receptor gamma), an HPAd are prescreened for Adipogenesis Signaling: Primary cultures of adipocytes are prepared by inducing differentiation of human primary preadipocytes and are prescreened for the expression of the following major adipocyte markers:
PPAR_ (Peroxisome proliferator-activated receptor gamma), an adipocyte-specific nuclear hormone receptor
C/EBPα (CCAAT/enhancer binding protein alpha), a transcription factor involved in creating and maintaining the adipocyte phenotype
IR (Insulin receptor), which plays a critical role in induction of adipocyte differentiation, as well as functional regulation
ACCα (Acetyl-CoA carboxylase alpha), a key enzyme for de novo fatty acid synthesis and lipogenic capability of adipocytes
GSK-3β (Glycogen synthase kinase-3-beta), a ubiquitous kinase implicated in regulation of adipocyte gene expression, signaling, adipogenesis, insulin action and glycogen synthesis
Adiponectin, a bioactive adipokine specifically secreted by differentiated adipocyte and involved in metabolic regulation... Read More | Bifidobacterium are Gram-positive, heterofermentative, anaerobic bacteria with a distinctive bifid; i.e. Y shape after which they are named. They wre originally isolated from the faeces of breast-fed infants, members of the genus Bifidobacterium are commonly found in the GI tract of mammals. In Bifidobacterium are Gram-positive, heterofermentative, anaerobic bacteria with a distinctive bifid; i.e. Y shape after which they are named. They wre originally isolated from the faeces of breast-fed infants, members of the genus Bifidobacterium are commonly found in the GI tract of mammals. In humans, Bifidobacterium resides within the GI tract, from birth to old age. Disturbances in the microbiota are linked to an ever-growing number of immune-linked disease states including IBD, atopic allergy, arthritis, and obesity. Therefore, there is a significant interest in treating these diseases through microbial or "probiotic" supplementation of patients, including Bifidobacterium. Data from mouse models and clinical trials indicate that Bifidobacterium may have beneficial effects for treating and preventing immune-linked diseases, including gut-associated and systemic conditions. Bifidobacterium have been commercially exploited as probiotic agents due to their associated health benefits and GRAS; Generally Recognised As Safe status.... Read More | The Eggerthellaceae are a family of Gram-positive, rod- or coccus-shaped Actinobacteria. It is the sole family within the order Eggerthellales. Members of this family are mostly anaerobic, non-motile, asaccharolytic and do not form spores. Eggerthellaceae species are commonly isolated from human andThe Eggerthellaceae are a family of Gram-positive, rod- or coccus-shaped Actinobacteria. It is the sole family within the order Eggerthellales. Members of this family are mostly anaerobic, non-motile, asaccharolytic and do not form spores. Eggerthellaceae species are commonly isolated from human and animal faeces and other human sources such as the colon, vagina, oral cavity and blood.... Read More | Creative Biolabs offers a range of recombinant cell lines for Immunotherapy discovery and development. | This product is a 43.2 kDa Human GRPR membrane protein expressed in in vitro wheat germ expression system with proprietary liposome technology. The protein is for research use only and is not approved for use in humans or in clinical diagnosis. |