| Description | The product SIRGT50946WQ is a type of small interfering RNA (siRNA) that targets BMT2 gene and regulates the expression of gene. The siRNA interferes with the expression of BMT2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is The product SIRGT50946WQ is a type of small interfering RNA (siRNA) that targets BMT2 gene and regulates the expression of gene. The siRNA interferes with the expression of BMT2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. The siRNA is systematically modified with the synthetic RNA-like high affinity nucleotide analogue, Locked Nucleic Acid (LNA), to improve its bio-stability, specificity and efficiency. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More | Bacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. BacteroidesBacteroides is a group of promising candidates that has attracted major attentions from scientists as model organisms or community for the investigations of the intestinal microbiota field, due to their powerful adaption characteristics in the host and especially the underlying benefits. Bacteroides is a genus of Gram-negative, obligate anaerobic bacteria. Bacteroides species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. Bacteroides; order is the most abundant group of Gram-negative bacteria which flourish in the human intestine at high densities of 109-1011 CFU per gram of feces, and constitutes over 30 species which are more closely related than members in other bacteria orders. And, Bacteroides is considered as one of the major genera of the core microbiota module, of which species with relative abundance of over 1% refers to B. uniformis, B. vulgatus, B. caccae, and B. thetaiotaomicron. In addition to the unique physiological characteristics and the special ecological dynamics, Bacteroides species are under investigations for their underlying beneficial dialogues with the host. Bacteroides species to be considered as next-generation probiotics, and the application of which in prevention or intervention in dysbiosis of gut microbiota and the associated disorders requires further investigations in the modulatory mechanisms and safety evaluation. Bacteroides is one of the dominant contributors of SCFA among the intestinal commensals, mostly in the form of acetate and propionate. Accumulated acetate blocks the transportation of toxins between gut lumen and blood, while propionate is capable of inducing the apoptosis of human colon carcinoma cells, and thus avoids the formation of tumors. Moreover, Vitamin K, which is mainly synthesized by gut microbiota candidates such as Bacteroides, can help prevent or treat osteoporosis by increasing bone mineral density.... Read More | This product is a 51.1 kDa Human RXFP3 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis. | Prevotella is a genus of anaerobic Gram-negative bacteria of the Bacteroidetes phylum, which also includes theclinically important genera Bacteroides and Porphyromonas. Prevotella strains are classically considered commensal bacteria due to their extensive presence inthe healthy human body and theirPrevotella is a genus of anaerobic Gram-negative bacteria of the Bacteroidetes phylum, which also includes theclinically important genera Bacteroides and Porphyromonas. Prevotella strains are classically considered commensal bacteria due to their extensive presence inthe healthy human body and their rare involvement ininfections. Prevotella spp. are members of the oral, vaginal, and gut microbiota and are often recovered from anaerobic infections of the respiratory tract. Prevotella spp. predominate in periodontal disease and periodontal abscesses. Regarding Prevotella, studies focused on the associations between the diverse species, genome and habitats with dietary patterns, health and disease. Evidence revealed beneficial effects of some Prevotella strains in the gut such as improving CVD risk factor profile and glucose metabolism. Most studies reported that vegetarians harbour higher numbers of Prevotella species as well as a high Prevotella/Bacteroides ratio compared with non-vegetarians; omnivores. Nevertheless, there is a need for more studies in humans to ascertain a causal and potential disease-triggering role for Prevotella and more in-depth metagenomic studies are needed in order to reveal the health- or disease-modulating properties.... Read More | The product SIRGT95067WQ is a type of small interfering RNA (siRNA) that targets Coq4 gene and regulates the expression of gene. The siRNA interferes with the expression of Coq4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has The product SIRGT95067WQ is a type of small interfering RNA (siRNA) that targets Coq4 gene and regulates the expression of gene. The siRNA interferes with the expression of Coq4 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More |