| Description | Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from normal Cynomolgus monkey pancreatic tissue. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from normal Cynomolgus monkey pancreatic tissue. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays such as cell-cell interaction, adhesion, migration, PCR, Western blot, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry, or generating cell derivatives for desired research applications.... Read More | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in autosomal-dominant familial Parkinson's disease with late onset (Fonzo et al., 2006, Thaler et al., 2009). The G2019S mutation increases the kinase activity of LRRK2 causing increased autophosphorylation and substrate phosphorylation that may affect neuronal cell health in Parkinson's disease patients (West et al., 2005).... Read More | Rhesus monkey is widely used in medical and biological research on human and animal related diseases even space travel due to its closeness to humans anatomically and physiologically. This product is purified from Rhesus monkey PBMCs by magnetic selection. Cells are negative for bacteria, yeast, Rhesus monkey is widely used in medical and biological research on human and animal related diseases even space travel due to its closeness to humans anatomically and physiologically. This product is purified from Rhesus monkey PBMCs by magnetic selection. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays such as cell-cell interaction, adhesion, migration, PCR, Western blot, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry, or generating cell derivatives for desired research applications.... Read More | Ruminococcus is a genus of bacteria in the class Clostridia. They are anaerobic, Gram-positive gut microbes. One or more species in this genus are found in significant numbers in the human gut microbiota. | The product SIRGT30937WQ is a type of small interfering RNA (siRNA) that targets ERN2 gene and regulates the expression of gene. The siRNA interferes with the expression of ERN2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has The product SIRGT30937WQ is a type of small interfering RNA (siRNA) that targets ERN2 gene and regulates the expression of gene. The siRNA interferes with the expression of ERN2 gene with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. It has potential applications in RNA interference (RNAi) and gene therapy development.... Read More |