| Description | Retinal pigment epithelium (RPE) is the layer of pigment cells that surrounds the neurosensory retina. These cells support the retinal visual cells, which attach to the choroid below and the visual cells of the upper layer of the retina. RPE has multiple functions: light absorption, epithelial Retinal pigment epithelium (RPE) is the layer of pigment cells that surrounds the neurosensory retina. These cells support the retinal visual cells, which attach to the choroid below and the visual cells of the upper layer of the retina. RPE has multiple functions: light absorption, epithelial transport, spatial ion buffer, visual circulation, phagocytosis, secretion and immune regulation. iNeu™ are retinal pigment epithelial cells derived from human iPSC. They express biomarkers such as RPE-65, RLBP1 and BEST.... Read More | Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from Cynomolgus monkey inferior vena cava.Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays such as Cynomolgus monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from Cynomolgus monkey inferior vena cava.Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays such as cell-cell interaction, adhesion, migration, PCR, Western blot, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry, or generating cell derivatives for desired research applications.... Read More | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in autosomal-dominant familial Parkinson's disease with late onset (Fonzo et al., 2006, Thaler et al., 2009). The G2019S mutation increases the kinase activity of LRRK2 causing increased autophosphorylation and substrate phosphorylation that may affect neuronal cell health in Parkinson's disease patients (West et al., 2005).... Read More | Creative Biolabs offers a range of recombinant cell lines for Immunotherapy discovery and development. | The Eggerthellaceae are a family of Gram-positive, rod- or coccus-shaped Actinobacteria. It is the sole family within the order Eggerthellales. Members of this family are mostly anaerobic, non-motile, asaccharolytic and do not form spores. Eggerthellaceae species are commonly isolated from human andThe Eggerthellaceae are a family of Gram-positive, rod- or coccus-shaped Actinobacteria. It is the sole family within the order Eggerthellales. Members of this family are mostly anaerobic, non-motile, asaccharolytic and do not form spores. Eggerthellaceae species are commonly isolated from human and animal faeces and other human sources such as the colon, vagina, oral cavity and blood.... Read More |