| Description | Rat hindbrain neurons (RHbN) are derived from the hindbrains of normal embryonic rats (the 15th day of pregnancy) by standard methods. When cultured under the recommended conditions, RHbN will categorize and form a complex neurite network within a week. RHbN is positive for βIII-Tubulin. | Alistipes is a relatively new genus of bacteria isolated primarily from medical clinical samples, although at a low rate compared to other genus members of the Bacteroidetes phylum, which are highly relevant in dysbiosis and disease. | Cynomolgus Monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from Cynomolgus Monkey fresh peripheral blood mononuclear cell under sterile conditions. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be Cynomolgus Monkey is widely used in medical experiments, especially those associated with neuroscience and disease. This product is isolated from Cynomolgus Monkey fresh peripheral blood mononuclear cell under sterile conditions. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of studies in immunology, infectious diseases, cancer therapy, etc.... Read More | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the G2019S mutation (GGC>AGC) in the LRRK2 gene. This line is homozygous for the G2019S mutation so both alleles contain the mutation.
The G2019S mutation in LRRK2 has been implicated in autosomal-dominant familial Parkinson's disease with late onset (Fonzo et al., 2006, Thaler et al., 2009). The G2019S mutation increases the kinase activity of LRRK2 causing increased autophosphorylation and substrate phosphorylation that may affect neuronal cell health in Parkinson's disease patients (West et al., 2005).... Read More | This product GTTS-WQ2724MR is a type of mRNA having 120 nt poly(A) tail and modified with Cap 1 & 5-Methyl-CTP & Pseudo-UTP. It ecodes the monoclonal antibody that targets IL23A gene. The antibody can be applied in Crohn's disease (CD) research. |