| Description | Marmoset monkeys are tree-dwelling small monkeys that habitat South American.This product is isolated from Marmoset monkey fresh whole blood tissue. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays such as cell-cell interaction, adhesion, Marmoset monkeys are tree-dwelling small monkeys that habitat South American.This product is isolated from Marmoset monkey fresh whole blood tissue. Cells are negative for bacteria, yeast, fungi, mycoplasma, and can be used for a variety of tests and assays such as cell-cell interaction, adhesion, migration, PCR, Western blot, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry, or generating cell derivatives for desired research applications.... Read More | Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the P301L mutation (CCG>CTG) into the MAPT gene. This line is homozygous for the P301L mutation so both alleles contain the mutation. Click on the product images to see the data and Human iPSC-Derived Neural Stem Cells that have been genetically edited using CRISPR-Cas9 technology to introduce the P301L mutation (CCG>CTG) into the MAPT gene. This line is homozygous for the P301L mutation so both alleles contain the mutation. Click on the product images to see the data and further details.
The P301L mutation MAPT has been implicated in frontotemporal dementia and parkinsonism (Dumanchin et al., 1998). The mutation affects only the 4R isoforms of MAPT since the exon containing the mutation is spliced out of 3R isoforms (Hutton et al., 1998). Aggregated MAPT/tau protein in affected patients consisted mainly of the 4R isoform (Hutton et al., 1998). The P301L mutation promotes aggregation of MAPT/tau protein into ordered paired helical filaments and beta sheet formation in vitro (von Bergen et al., 2001).... Read More | Creative Biolabs offers the overexpression HEK293 cells stably expressing additional TLR or NOD genes. | This product GTTS-WK5967MR is a type of mRNA having 30 nt poly(A) tail and modified with Cap 1 & N1-Methylpseudo-UTP. It ecodes the CD40 protein. This product can be used in -related researches. | Rat Schwann cells (RSC) are the main glial cells in the peripheral nervous system, providing physical and chemical support for neurons. Myelin Schwann cells form an insulating sheath around neuron cell bodies (sensory ganglia) and fibers (sensory nerves and motor neurons). Regular exposure of the Rat Schwann cells (RSC) are the main glial cells in the peripheral nervous system, providing physical and chemical support for neurons. Myelin Schwann cells form an insulating sheath around neuron cell bodies (sensory ganglia) and fibers (sensory nerves and motor neurons). Regular exposure of the axon membrane to the extracellular space (myelin sheath space) at the Raniver node allows the action potential to propagate quickly along the axon. RSC is important for the morphology, survival and growth of axons and neurons. Studies have also shown that Schwann cells can promote neuronal recovery and experimental spinal cord regeneration.... Read More |